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Recombinant Human YWHAH protein

Cat.No. : YWHAH-67H
Product Overview : Recombinant Human 14-3-3 eta was expressed in E.coli and purified by using conventional chromatography techniques.
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  • Gene Information
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Description : 14-3-3 eta also as known as YWHAH. This protein belong to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. 14-3-3 eta interacts with and relocalizes the A20 zinc finger protein from the insoluble to the soluble fraction, suggesting a chaperone function. It implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binding to a large number of partners, usually by recognition of a phosphothreonine motif.
Source : E. coli
Species : Human
Form : Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.
Molecular Mass : 28.2kDa (246aa)
AA Sequence : MGDREQLLQR ARLAEQAERY DDMASAMKAV TELNEPLSNE DRNLLSVAYK NVVGARRSSW RVISSIEQKT MADGNEKKLE KVKAYREKIEKELETVCNDV LSLLDKFLIK NCNDFQYESK VFYLKMKGDY YRYLAEVASG EKKNSVVEAS EAAYKEAFEI SKEQMQPTHP IRLGLALNFS VFYYEIQNAP EQACLLAKQA FDDAIAELDT LNEDSYKDST LIMQLLRDNL TLWTSDQQDE EAGEGN
Purity : >90% by SDS - PAGE
Storage : Can be stored at +4centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20Centigrade or -70Centigrade. Avoid repeated freezing and thawing cycles.
Concentration : 1mg/ml (determined by Absorbance at 280nm)
Gene Name : YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide [ Homo sapiens ]
Official Symbol : YWHAH
Synonyms : YWHAH; YWHA1; 14-3-3 protein eta; 14 3 3 eta
Gene ID : 7533
mRNA Refseq : NM_003405
Protein Refseq : NP_003396
MIM : 113508
UniProt ID : Q04917
Chromosome Location : 22q12.1-q13.1
Pathway : Alpha6-Beta4 Integrin Signaling Pathway, organism-specific biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; Calcium Regulation in the Cardiac Cell, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, conserved biosystem; Class I PI3K signaling events mediated by Akt, organism-specific biosystem; ErbB1 downstream signaling, organism-specific biosystem;
Function : actin binding; enzyme binding; glucocorticoid receptor binding; insulin-like growth factor receptor binding; protein binding; protein domain specific binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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