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Official Full Name actin-like 6B
Background The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a subunit of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. This subunit may be involved in the regulation of genes by structural modulation of their chromatin, specifically in the brain.
Synonyms ACTL6B; actin-like 6B; actin like 6 , ACTL6; actin-like protein 6B; BAF53B; arpNalpha; hArpN alpha; actin-like 6; BRG1-associated factor 53B; actin-related protein Baf53b; 53 kDa BRG1-associated factor B; ACTL6
    • Species :
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • E.Coli or Yeast
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ACTL6B-301380H Recombinant Human ACTL6B protein, GST-tagged E.coli GST
    Human ACTL6B-223H Recombinant Human ACTL6B Protein, GST-tagged Wheat Germ GST
    Human ACTL6B-26300TH Recombinant Human ACTL6B, His-tagged E.coli His
    Human ACTL6B-9060HCL Recombinant Human ACTL6B 293 Cell Lysate HEK293 N/A
    Mouse ACTL6B-1245M Recombinant Mouse ACTL6B Protein Mammalian Cell His
    Rat Actl6b-3101R Recombinant Rat Actl6b, His-tagged E.Coli or Yeast His
    Rat ACTL6B-482R Recombinant Rat ACTL6B Protein Mammalian Cell His
    Rhesus Macaque ACTL6B-223R Recombinant Rhesus monkey ACTL6B Protein, His-tagged Mammalian Cell His
    Zebrafish ACTL6B-2883Z Recombinant Zebrafish ACTL6B Mammalian Cell His

    ACTL6B involved in several pathways and played different roles in them. We selected most pathways ACTL6B participated on our site, such as Chromatin modifying enzymes, Chromatin organization, Prostate Cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with ACTL6B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Chromatin modifying enzymes ACTL6A; KDM5C; C17orf81; KAT5; MSL3; KDM4B; PHF17; SAP30L; KDM3A; KDM2A
    Chromatin organization KAT8; ELP4; EHMT2; SMARCC2; JADE1; ING4; RBBP4; SMARCC1; KDM5C; TAF6L
    Prostate Cancer LEF1; INSRR; TCF7L2; ERBB2; MTOR; SPINK1; NKX3-1; GSTP1; INS1; CREB3L2
    RMTs methylate histone arginines SMARCE1; ARID1A; PRMT5; SMARCC1B; ACTL6B; PRMT6; SMARCD3B; SMARCA4; SMARCB1A; SMARCC2

    ACTL6B has several biochemical functions, for example, structural constituent of cytoskeleton, transcription coactivator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ACTL6B itself. We selected most functions ACTL6B had, and list some proteins which have the same functions with ACTL6B. You can find most of the proteins on our site.

    Function Related Protein
    structural constituent of cytoskeleton EPB41; BFSP1; EPB42; ANK1; ACTL7B; TUBA3E; TUBA1B; TUBB2; ATXN1; VILL
    transcription coactivator activity RBPMS; TCERG1; CREBBP; AIP; SUB1B; GTF2A2; HSF2; MAML2; TADA2B; NR2C2

    ACTL6B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ACTL6B here. Most of them are supplied by our site. Hope this information will be useful for your research of ACTL6B.


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