Recombinant Rat ACTL6B Protein
Cat.No. : | ACTL6B-482R |
Product Overview : | Recombinant Rat ACTL6B full length or partial length protein was expressed. |
- Specification
- Gene Information
- Related Products
Source : | Mammalian Cells |
Species : | Rat |
Tag : | His |
Form : | Liquid or lyophilized powder |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method. |
Purity : | >80% |
Notes : | This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications. |
Storage : | Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC. |
Storage Buffer : | PBS buffer |
Gene Name : | Actl6b actin-like 6B [ Rattus norvegicus ] |
Official Symbol : | ACTL6B |
Gene ID : | 288563 |
mRNA Refseq : | NM_001105917.1 |
Protein Refseq : | NP_001099387.2 |
MIM : | |
UniProt ID : | P86173 |
Products Types
◆ Recombinant Protein | ||
ACTL6B-51R | Recombinant Rhesus Macaque ACTL6B Protein, His (Fc)-Avi-tagged | +Inquiry |
ACTL6B-286M | Recombinant Mouse ACTL6B Protein, His (Fc)-Avi-tagged | +Inquiry |
ACTL6B-138R | Recombinant Rat ACTL6B Protein, His (Fc)-Avi-tagged | +Inquiry |
ACTL6B-223R | Recombinant Rhesus monkey ACTL6B Protein, His-tagged | +Inquiry |
Actl6b-3101R | Recombinant Rat Actl6b, His-tagged | +Inquiry |
◆ Lysates | ||
ACTL6B-9060HCL | Recombinant Human ACTL6B 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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- Q&As
- Reviews
Q&As (21)
Ask a questionWhile the main known interacting partners of ACTL6B are within the nBAF complex, additional interactions with other proteins or complexes have not been extensively characterized.
Yes, ACTL6B is implicated in neuronal development and differentiation, as it is required for proper chromatin remodeling during neuronal maturation.
ACTL6B is evolutionarily conserved across different species, indicating its functional importance throughout evolution.
Alternative splicing variants of ACTL6B have not been widely reported in the literature. The majority of studies focus on the canonical isoform of ACTL6B.
Specific post-translational modifications of ACTL6B, such as phosphorylation or acetylation, have not been extensively studied.
ACTL6B loss is a significant cause of recessive ASD, suggesting its involvement in the development of this disorder.
ACTL6B plays a role in chromatin remodeling, gene regulation, and transcriptional control in various cell types, particularly in postmitotic neurons.
Yes, ACTL6B shares structural similarities with other actin-like proteins, including the presence of an actin fold and conserved residues involved in protein-protein interactions.
ACTL6B is primarily localized in the nucleus, where it exerts its functions in chromatin remodeling and gene regulation.
ACTL6B, as part of the nBAF complex, is involved in chromatin remodeling and gene regulation, particularly in postmitotic neurons. It plays a role in shaping the chromatin landscape and influencing cellular processes related to neuronal development and function.
ACTL6B belongs to the actin-like protein family, which comprises proteins that share structural similarities with actin but may have distinct functions and roles in cellular processes.
Yes, ACTL6B has a paralog called ACTL6A (Actin-like 6A), which shares similarities in structure and function.
Currently, there are no specific genetic disorders linked to ACTL6B mutations
The nBAF complex, including ACTL6B, plays a role in modifying the structure of chromatin, allowing for proper gene regulation and functional changes in postmitotic neurons.
ACTL6B is a component of the neuronal BRG1/brm-associated factor (nBAF) complex, which is required for chromatin remodeling specifically in postmitotic neurons.
Yes, ACTL6B interacts with other proteins within the neuronal BRG1/brm-associated factor (nBAF) complex, including various subunits involved in chromatin remodeling and gene regulation.
While the main known interacting partners of ACTL6B are within the nBAF complex, additional interactions with other proteins or complexes have not been extensively characterized.
Targeting ACTL6B or the nBAF complex could hold therapeutic potential for ASD; however, further research is needed to understand the precise mechanisms involved and to evaluate the feasibility and effectiveness of such targeting approaches.
ACTL6B is widely expressed in various tissues, but its expression is particularly prominent in the brain, where it plays a crucial role in neuronal development and function.
Impaired neuron-specific chromatin repression is proposed as a potential mechanism underlying the association between ACTL6B loss and ASD.
ACTL6B belongs to the actin-like protein family and has a conserved structure similar to actin proteins. It consists of a globular domain and a flexible C-terminal tail.
Customer Reviews (5)
Write a reviewIncreased protein expression, enhanced cell proliferation, or inhibition of specific biological processes, when using this protein.
The packaging includes proper labeling and documentation, facilitating easy identification and handling of the protein product upon arrival.
They have provided valuable technical guidance and troubleshooting assistance, helping us optimize our experimental protocols and achieve better results.
We have successfully replicated our findings using multiple batches of the protein product, indicating its reliable and consistent behavior.
The protein product is produced using state-of-the-art manufacturing techniques, ensuring consistent quality and performance.
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