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Official Full Name activin A receptor, type IC
Background ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM, Mar 2008]
Synonyms ACVR1C; activin A receptor, type IC; ALK7; ACVRLK7; activin receptor type-1C; ALK-7; ACTR-IC; activin receptor type IC; activin receptor-like kinase 7;
    • Species :
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Human Cell
    • Mammalian Cell
    • NS0
    • NSO
    • Sf9 Insect Cell
    • Wheat Germ
    • Tag :
    • Fc
    • GST
    • His
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ACVR1C-1019H Recombinant Human ACVR1C Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human ACVR1C-189H Recombinant Human v protein, GST/His-tagged E.coli GST/His
    Human ACVR1C-252H Recombinant Human ACVR1C Protein, GST-tagged Wheat Germ GST
    Human ACVR1C-255H Recombinant Human ACVR1C Protein, Fc-tagged HEK293 Fc
    Human ACVR1C-289H Recombinant Human ACVR1C Protein, His-tagged E.coli His
    Human ACVR1C-5045H Recombinant Human ACVR1C Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human ACVR1C-530H Recombinant Human ACVR1C, Fc-tagged, Biotinylated Human Cell Fc
    Human ACVR1C-531H Recombinant Human ACVR1C, Fc-tagged Human Cell Fc
    Human ACVR1C-6996H Recombinant Human ALK7, GST-tagged Sf9 Insect Cell GST
    Human ACVR1C-9356H Recombinant Human ACVR1C, GST-tagged E.coli GST
    Human ALK7-3271H Recombinant Human ALK7, GST-tagged Sf9 Insect Cell GST
    Mouse Acvr1c-1523M Recombinant Mouse Acvr1c Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Rat ACVR1C-493R Recombinant Rat ACVR1C Protein Mammalian Cell His
    Rat Acvr1c-502R Recombinant Rat Activin A Receptor, Type IC NSO N/A
    Rat Acvr1c-822R Recombinant Rat Acvr1c Protein, Fc Chimera NS0 Fc
    Cynomolgus Monkey ACVR1C-1277CCL Recombinant Cynomolgus ACVR1C cell lysate Human Cell N/A
    Cynomolgus Monkey ACVR1C-8816C Recombinant Cynomolgus ACVR1C, Fc tagged Human Cell Fc
    Rhesus Macaque ACVR1C-232R Recombinant Rhesus monkey ACVR1C Protein, His-tagged Mammalian Cell His

    acvr1c involved in several pathways and played different roles in them. We selected most pathways acvr1c participated on our site, such as Developmental Biology, MAPK signaling pathway, Regulation of signaling by NODAL, which may be useful for your reference. Also, other proteins which involved in the same pathway with acvr1c were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Developmental Biology NRP2; PLXND1; RHOB; ACTR2B; MYL12B; SCN3A; CSNK2B; MED15; MEF2B; SEMA3A
    MAPK signaling pathway HRASA; ARR3A; RASA1; GADD45AB; CACNA2D3; PDGFAB; MAP4K3; RAC3A; ATF4B1; NFATC1
    Regulation of signaling by NODAL CFC1; ACVR1C; TDGF1; LEFTY1
    Signal Transduction CHRDL1; PCSK6; CRHR2; RGS10; STRA6; CCL35.2; MKS1; DRAP1; METAP2B; PROKR1A
    Signaling by Activin DRAP1; INHBAA; FSTL3; ACVR1C; FST; FOXH1; FSTB
    Signaling by NODAL PCSK6; FOXH1; GDF1; DRAP1; TDGF1; CFC1; ACVR1C; LEFTY1
    Signaling pathways regulating pluripotency of stem cells FZD2; REST; NANOG; LIFR; BMPR2; ID4; PIK3R5; WNT5B; GSK3B; ZFHX3
    TGF-beta signaling pathway BMPR2A; PPP2CB; LEFTY1; SMAD3; THBS1; SMAD7B; AMHR2; TGFBR1A; GDF5; BMPR1BB

    acvr1c has several biochemical functions, for example, ATP binding, activin receptor activity, type I, growth factor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by acvr1c itself. We selected most functions acvr1c had, and list some proteins which have the same functions with acvr1c. You can find most of the proteins on our site.

    Function Related Protein
    activin receptor activity, type I ACVR1B; ACVRL1; ACVR1C
    growth factor binding GHRHR; RHBDF2; TEK; IL6ST; FLT1; HTRA1B; SDCBP; LTBP2; A2M; ACVR1C
    metal ion binding NPAS2; MUL1A; RNF150; OAS1; ZBTB12; MMP23BB; ZNF781; COL1A1; IKZF5; FTR54
    nodal binding ACVR1C; CFC1
    receptor signaling protein serine/threonine kinase activity BMPR1AB; BMPR1AA; TGFBR1; SLKA; ACVR1L; TGFBR1B; STK25B; ACVR2B; ACVR2A; ACVR1C

    acvr1c has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with acvr1c here. Most of them are supplied by our site. Hope this information will be useful for your research of acvr1c.

    b4dyc6_human; HSP90AB1; INHBB

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