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Recombinant Human ACVR1C Protein, GST-tagged

Cat.No. : ACVR1C-252H
Product Overview : Human ACVR1C full-length ORF ( AAH22530.1, 1 a.a. - 493 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
  • Related Products
Description : ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM, Mar 2008]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 79.97 kDa
AA Sequence : MTRALCSALRQALLLLAAAAELSPG LKCVCLLCDSSNFTCQTEGACWASV MLTNGKEQVIKSCVSLPELNAQVFC HSSNNVTKTECCFTDFCNNITLHLP TASPNAPKLGPMELAIIITVPVCLL SIAAMLTVWACQGRQCSYRKKKRPN VEEPLSECNLVNAGKTLKDLIYDVT ASGSGSGLPLLVQRTIARTIVLQEI VGKGRFGEVWHGRWCGEDVAVKIFS SRDERYWFREAEIYQTVMLRHENIL GFIAADNKDNGTWTQLWLVSEYHEQ GSLYDYLNRNIVTMAGMIKLALSIA SGLAHLHMEIVGTQGKPAIAHRDIK SKNILVKKCETCAIADLGLAVKHDS ILNTIDIPQNPKVGTKRYMAPEMLD DTMNVNIFESFKRADIYSVGLVYWE IARRCSVGGIVEEYQLPYYDMVPSD PSIEEMRKVVCDQKFRPSIPNQWQS CEALRVMGRIMRECWYANGAARLTA LRIKKTISQLCVKEDCKA
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : ACVR1C activin A receptor, type IC [ Homo sapiens ]
Official Symbol : ACVR1C
Synonyms : ACVR1C; activin A receptor, type IC; activin receptor type-1C; ACVRLK7; ALK7; ALK-7; ACTR-IC; activin receptor type IC; activin receptor-like kinase 7;
Gene ID : 130399
mRNA Refseq : NM_001111031
Protein Refseq : NP_001104501
MIM : 608981
UniProt ID : Q8NER5

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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