Recombinant Human v protein, GST/His-tagged

• Cat.No.: ACVR1C-189H
• Product Overview: Recombinant Human ACVR1C, transcript variant 1, fused with GST tag at N-terminal and His tag at C-terminal was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: GST&His
• Protein Length: 1-493aa
• Description: ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).
• Form: 25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1%Sarkosyl.
• Molecular Mass: 82.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: ACVR1C activin A receptor, type IC [ Homo sapiens ]
• Official Symbol: ACVR1C
• Synonyms: ACVR1C; activin A receptor, type IC; activin receptor type-1C; ACVRLK7; ALK7; ALK-7; ACTR-IC; activin receptor type IC; activin receptor-like kinase 7
• Gene ID: 130399
• mRNA Refseq: NM_145259
• Protein Refseq: NP_660302
• MIM: 608981
• UniProt ID: Q8NER5