Recombinant Human ACVR1C Protein, His-tagged

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Recombinant Human ACVR1C Protein, His-tagged

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Cat.No. : ACVR1C-289H
Product Overview : Recombinant Human ACVR1C(Glu21~Ala493) fused with His tag at N-terminal was expressed in E. coli.
Description : ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).
Source : E. coli
Species : Human
Tag : His
Form : PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Molecular Mass : 56.5kDa
Protein length : Glu21~Ala493
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : > 90%
Applications : Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Reconstitution : Reconstitute in PBS or others
Figure :

Gene Name : ACVR1C activin A receptor, type IC [ Homo sapiens ]
Official Symbol : ACVR1C
Synonyms : ACVR1C; activin A receptor, type IC; activin receptor type-1C; ACVRLK7; ALK7; ALK-7; ACTR-IC; activin receptor type IC; activin receptor-like kinase 7;
Gene ID : 130399
mRNA Refseq : NM_001111031
Protein Refseq : NP_001104501
MIM : 608981
UniProt ID : Q8NER5
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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