Active Recombinant Human ACVR1C Protein, GST-tagged

• Cat.No.: ACVR1C-6903H
• Product Overview: Active Recombinant Human ACVR1C Protein, GST-tagged was expressed in baculovirus expression system.

Specification

• Species: Human
• Source: Insect cells
• Tag: GST
• Protein Length: 139-493 aa
• Description: Cytoplasmic domain of human ACVR1C [139-493(end) amino acids of accession number NP_660302.2] was expressed as N-terminal GST-fusion protein(67 kDa) using baculovirus expression system. GSTACVR1C was purified by using glutathione sepharose chromatography.
• Tag: N-GST
• Molecular Mass: 67 kDa
• Purity: 61 % by SDS-PAGE/CBB staining
• Handling: Avoid repeating freeze-thaws.
• Storage: Store at -80 °C.
• Storage Buffer: 50 mM Tris-HCl, 150 mM NaCl, 0.05% Brij35, 1 mM DTT, 10% glycerol, pH7.5
• References: Kim, Byung-Chul et al. "Activin receptor-like kinase-7 induces apoptosis through activation of MAPKs in a Smad3-dependent mechanism in hepatoma cells." The Journal of biological chemistry vol. 279,27 (2004): 28458-65.

Gene Information

• Gene Name: ACVR1C activin A receptor type 1C [ Homo sapiens (human) ]
• Official Symbol: ACVR1C
• Synonyms: ACVR1C, ACVRLK7, ALK7
• Gene ID: 130399
• mRNA Refseq: NM_145259
• Protein Refseq: NP_660302.2
• MIM: 608981
• UniProt ID: Q8NER5