|Official Full Name||aldo-keto reductase family 1, member B10 (aldose reductase)|
|Background||This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member can efficiently reduce aliphatic and aromatic aldehydes, and it is less active on hexoses. It is highly expressed in adrenal gland, small intestine, and colon, and may play an important role in liver carcinogenesis. [provided by RefSeq, Jul 2008]|
|Synonyms||AKR1B10; aldo-keto reductase family 1, member B10 (aldose reductase); HIS; HSI; ARL1; ARL-1; ALDRLn; AKR1B11; AKR1B12; aldo-keto reductase family 1 member B10; ARP; hARP; SI reductase; aldose reductase-like 1; small intestine reductase; aldose reductase-like peptide; aldose reductase-related protein; aldo-keto reductase family 1, member B11 (aldose reductase-like);|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
AKR1B10 involved in several pathways and played different roles in them. We selected most pathways AKR1B10 participated on our site, such as Pentose and glucuronate interconversions, Fructose and mannose metabolism, Galactose metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with AKR1B10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Pentose and glucuronate interconversions||UGT1A2; RPE; UGT2B7; UGT1A6A; UGT1A6B; UGT1A6; UGT1A4; AKR1B8; UGT1A7C; AKR1B10|
|Fructose and mannose metabolism||PFKFB1; FBP1; ALDOCB; GMDS; ALDOB; TIGARB; AKR1B1L; TIGARA; PFKFB2A; PFKFB4L|
|Galactose metabolism||G6PC3; AKR1B7; GLB1; GALM; UGP2B; G6PC; HK3; B4GALT1; AKR1B1L; aLA|
|Glycerolipid metabolism||MBOAT2; DGKB; LPIN1; GLYCTK; PPAP2C; PNLIPRP3; GPAM; ALDH1B1; LIPC; DGAT2|
|Metabolic pathways||AGL; HMGCR; HSD17B1; RABGNT1; NAGK; CYP26A1; PIGN; CMAS; HIBADH; PHYKPL|
AKR1B10 has several biochemical functions, for example, aldo-keto reductase (NADP) activity, geranylgeranyl reductase activity, indanol dehydrogenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by AKR1B10 itself. We selected most functions AKR1B10 had, and list some proteins which have the same functions with AKR1B10. You can find most of the proteins on our site.
|aldo-keto reductase (NADP) activity||AKR1B1; SPR; SDR42E1; H2-KE6; HSD3B6; KCNAB2; AKR1C21; HSD11B1LA; HSD3B5; SDR16C6|
|geranylgeranyl reductase activity||AKR1B8; AKR1C3; AKR1B10|
|indanol dehydrogenase activity||AKR1C3; AKR1B10; AKR1B8|
|protein binding||NOA1; TNFSF10; ZFC3H1; IKBKB; SUPT4H1; FAP; LSM10; COPS7A; LAGE3; ACTN3|
|retinal dehydrogenase activity||AKR1C6; Aldh1a7; ALDH1A1; AKR1C4; AKR1B10; ALDH8A1; ALDH1A3; AKR1C3; AKR1B8|
AKR1B10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AKR1B10 here. Most of them are supplied by our site. Hope this information will be useful for your research of AKR1B10.
ACACA; TERF2IP; Nedd1; Jup; Slain1; TSNAX