AP1S1

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AP1S1

Official Full Name adaptor-related protein complex 1, sigma 1 subunit
Background The protein encoded by this gene is part of the clathrin coat assembly complex which links clathrin to receptors in coated vesicles. These vesicles are involved in endocytosis and Golgi processing. This protein, as well as beta-prime-adaptin, gamma-adaptin, and the medium (mu) chain AP47, form the AP-1 assembly protein complex located at the Golgi vesicle.
Synonyms AP1S1; adaptor-related protein complex 1, sigma 1 subunit; CLAPS1; AP-1 complex subunit sigma-1A; AP 1 complex subunit sigma 1A; AP19; clathrin assembly protein complex 1 sigma 1A small chain; clathrin coat assembly protein AP19; clathrin associated/assembly/adaptor protein; small 1 (19kD); golgi adaptor HA1/AP1 adaptin sigma 1A subunit; HA1 19 kDa subunit; SIGMA1A; sigma1A subunit of AP 1 clathrin adaptor complex; sigma1A adaptin; WUGSC:H_DJ0747G18.2; Adapter related protein complex 1 sigma 1A subunit; Adapter-related protein complex 1 sigma-1A subunit; Adaptor protein complex AP-1 sigma-1A subunit; Adaptor protein complex AP1 sigma 1A subunit; AP1 complex subunit sigma 1A; AP1S1_HUMAN; Clathrin assembly protein complex 1 sigma-1A small chain; Golgi adaptor HA1/AP1 adaptin sigma-1A subunit; Sigma 1a subunit of AP-1 clathrin; Sigma 1a subunit of AP1 clathrin; Sigma adaptin 1A; Sigma-adaptin 1A; Sigma1A-adaptin; sigma1A subunit of AP-1 clathrin adaptor complex; clathrin-associated/assembly/adaptor protein, small 1 (19kD)
    • Species :
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E.Coli or Yeast
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human AP1S1-27354TH Recombinant Human AP1S1 Wheat Germ N/A
    Human AP1S1-649H Recombinant Human AP1S1 protein, GST-tagged Wheat Germ GST
    Human AP1S1-8817HCL Recombinant Human AP1S1 293 Cell Lysate HEK293 N/A
    Mouse AP1S1-1735M Recombinant Mouse AP1S1 Protein Mammalian Cell His
    Mouse Ap1s1-3529M Recombinant Mouse Ap1s1, His-tagged E.Coli or Yeast His
    Zebrafish AP1S1-10638Z Recombinant Zebrafish AP1S1 Mammalian Cell His

    AP1S1 involved in several pathways and played different roles in them. We selected most pathways AP1S1 participated on our site, such as Adaptive Immune System, Clathrin derived vesicle budding, Disease, which may be useful for your reference. Also, other proteins which involved in the same pathway with AP1S1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adaptive Immune System CTSL1; MICA; KIF11; TRIM39; KLB; SRMS; CTSH; FBXO44; DCTN3; LILRB5
    Clathrin derived vesicle budding DTNBP1B; PICALM; FTH1B; AP1G1; SH3D19; ARF1; BLOC1S4; BLOC1S6; PUM1; YIPF6
    Disease gag; IPO5; JAG2; SFTPC; CUX1; CCNC; TRAT1; CTDP1; FDX1; TICAM1
    Golgi Associated Vesicle Biogenesis BLOC1S4; PLDN; AP1M2; SNX9B; CPD; AP1G1; TFR1B; AP1S3A; PICALM; TBC1D8B
    HIV Infection ELL; TCEB3; PDCD6IP; AP1M2; DOCK2; PACS1; TAF1L; NPM1; SSRP1; RCC1
    Host Interactions of HIV factors PSIP1; PPIAL4A; APOBEC3G; PACS1; DOCK2; AP1G1; RCC1; AP1S1; AP1B1; AP1M2
    Immune System BTR16; POLR3G; ACTR1B; ASB11; FCN1; TREML1; TRIM68; KIF4; CLEC2H; OASL
    Infectious disease IPO5; PPIAL4A; NMT1; VPS37A; RCC1; APOBEC3G; AP1S1; PDCD6IP; CCDC167; STX1B

    AP1S1 has several biochemical functions, for example, protein transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by AP1S1 itself. We selected most functions AP1S1 had, and list some proteins which have the same functions with AP1S1. You can find most of the proteins on our site.

    Function Related Protein
    protein transporter activity RAMP3; RAB4A; PPIAL4A; RUFY1; TNPO1; VPS35; IPO5; ITGB1BP1; ARFGAP3; AP4B1

    AP1S1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AP1S1 here. Most of them are supplied by our site. Hope this information will be useful for your research of AP1S1.

    AP1B1; Ap1g1; SLC16A1; AP1S2; RAB10; SEC61A1; IKBKE; ARMC6; EBLN2; pi3p; GTSE1

    Stratta, P; Merlotti, G; et al. Calcium-sensing-related gene mutations in hypercalcaemic hypocalciuric patients as differential diagnosis from primary hyperparathyroidism: detection of two novel inactivating mutations in an Italian population. NEPHROLOGY DIALYSIS TRANSPLANTATION 29:1902-1909(2014).
    Kim, YA; Choi, HJ; et al. Replication of Caucasian loci associated with bone mineral density in Koreans. OSTEOPOROSIS INTERNATIONAL 24:2603-2610(2013).

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