ARF6 Protein


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Official Full Name ADP-ribosylation factor 6
Background ADP-ribosylation factor (Arf) proteins are low molecular weight GTP binding proteins that belong to the Ras GTPase superfamily. Arf proteins are grouped into three distinct classes based on amino acid sequence and structural similarity, with Arf6 as the s
Synonyms ARF6; ADP-ribosylation factor 6; DKFZp564M0264
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • E.Coli or Yeast
    • HEK293
    • HEK293T
    • In Vitro Cell Free System
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • His-SUMO
    • MYC/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ARF6-26533TH Recombinant Human ARF6 protein, His-tagged E.coli His
    Human ARF6-3369H Recombinant Human ADP-ribosylation Factor 6, His-tagged E.coli His
    Human ARF6-749H Recombinant Human ARF6 protein, GST-tagged Wheat Germ GST
    Human ARF6-9803H Recombinant Human ARF, His-tagged E.coli His
    Mouse ARF6-1842M Recombinant Mouse ARF6 Protein Mammalian Cell His
    Mouse Arf6-3210M Recombinant Mouse Arf6, His-tagged E.Coli or Yeast His
    Rat ARF6-752R Recombinant Rat ARF6 Protein Mammalian Cell His
    Rhesus Macaque ARF6-380R Recombinant Rhesus monkey ARF6 Protein, His-tagged Mammalian Cell His
    Chicken ARF6-3667C Recombinant Chicken ARF6 Mammalian Cell His
    Human ARF6-8756HCL Recombinant Human ARF6 293 Cell Lysate HEK293 N/A
    Human ARF6-1184HF Recombinant Full Length Human ARF6 Protein, GST-tagged In Vitro Cell Free System GST
    Human ARF6-2545H Recombinant Human ARF6 protein, His-SUMO-tagged E.coli His-SUMO
    Human ARF6-2595H Recombinant Human ARF6 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Arf6-638M Recombinant Mouse Arf6 Protein, MYC/DDK-tagged HEK293T MYC/DDK

    ARF6 involved in several pathways and played different roles in them. We selected most pathways ARF6 participated on our site, such as Ras signaling pathway, Phospholipase D signaling pathway, Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with ARF6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Ras signaling pathway PIK3CB; CALML3; KITLG; REL; RALGDS; RASA1; RASAL1; SHC3; CALM3; IGF1
    Phospholipase D signaling pathway CYTH4; INS; CYTH3; PLA2G4D; PPAP2B; LPAR6; SHC2; PIK3R3; GRB2; INS1
    Fc gamma R-mediated phagocytosis VAV1; PIK3R3; PRKCD; RAC1; LIMK1; PAK1; LYN; PRKCE; MAPK1; PRKCG

    ARF6 has several biochemical functions, for example, GTP binding, GTPase activity, protein N-terminus binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ARF6 itself. We selected most functions ARF6 had, and list some proteins which have the same functions with ARF6. You can find most of the proteins on our site.

    Function Related Protein
    GTPase activity GBP1; TUBB; TUBA7L; TUBB1; GNB1; RAB3C; MTG1; ARF4; GNAV1; DIRAS1
    protein N-terminus binding MAP2K1; HDAC1; ERCC6; PHB2; VPS25; SCFD1; SYNGR3; TBL1XR1; KCNB1; GTF2H2
    protein binding DPY30; MORN4; TRIM16; PUM1; ORC1L; BAG3; LEPROT; SYCE1; NR4A3; CLUAP1
    thioesterase binding TRAF5; CDC42; TRAF2; TRAF3; CALM1; CALM3; TRAF4; RAC1; TRAF1; CALM2

    ARF6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARF6 here. Most of them are supplied by our site. Hope this information will be useful for your research of ARF6.


    van den Bosch, MTJ; Poole, AW; et al. Cytohesin-2 phosphorylation by protein kinase C relieves the constitutive suppression of platelet dense granule secretion by ADP-ribosylation factor 6. JOURNAL OF THROMBOSIS AND HAEMOSTASIS 12:726-735(2014).
    Karnik, R; Ludlow, MJ; et al. Endocytosis of hERG Is Clathrin-Independent and Involves Arf6. PLOS ONE 8:-(2013).

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