Human ARF6 Knockdown Cell Lysate

• Cat.No.: ARF6-050HKCL
• Product Overview: WB-validated ARF6 Knockdown HeLa Cell Lysate

Specification

• Species: Human
• Source: HeLa
• Tag: Non
• Description: This gene encodes a member of the human ARF gene family, which is part of the RAS superfamily. The ARF genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The product of this gene is localized to the plasma membrane, and regulates vesicular trafficking, remodelling of membrane lipids, and signaling pathways that lead to actin remodeling. A pseudogene of this gene is located on chromosome 7.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 20 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HeLa cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HeLa cell lysate 1 vial of 100 μg ARF6 KD HeLa cell lysate
• Protein Pathways: Endocytosis, Fc gamma R-mediated phagocytosis
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: ARF6 ADP-ribosylation factor 6 [ Homo sapiens (human) ]
• Official Symbol: ARF6
• Synonyms: ARF6; ADP-ribosylation factor 6; DKFZp564M0264
• Gene ID: 382
• mRNA Refseq: NM_001663
• Protein Refseq: NP_001654
• MIM: 600464
• UniProt ID: P62330