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Official Full Name bone morphogenetic protein receptor, type II (serine/threonine kinase)
Background BMPR2 is a type II serine/threonine receptor kinase that binds to an array of secreted bone morphogenetic proteins (BMPs). BMPs belong to the superfamily of TGF-beta ligands that modulate gastrulation, neurogenesis, chondrogenesis, interdigital cell death
Synonyms BMPR2; bone morphogenetic protein receptor, type II (serine/threonine kinase); PPH1, primary pulmonary hypertension 1; bone morphogenetic protein receptor type-2; BMPR II; BMPR3; BRK 3; T ALK; BMPR-2; BMP type-2 receptor; BMP type II receptor; type II ac
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • Human Cell
    • Mammalian Cell
    • Sf21 Insect Cell
    • Sf9 Insect Cell
    • Wheat Germ
    • Tag :
    • Fc
    • His
    • GST
    • T7
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human BMPR2-10258H Recombinant Human BMPR2, His-tagged E.coli His
    Human BMPR2-133H Recombinant Human BMPR2, Fc-His tagged Human Cell Fc/His
    Human BMPR2-134H Recombinant Human BMPR2, His tagged Human Cell His
    Human BMPR2-1367H Recombinant Human BMPR2 (Active), His-tagged Sf9 Insect Cell His
    Human BMPR2-2707H Recombinant Human BMPR2 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human BMPR2-2717HCL Recombinant Human BMPR2 cell lysate Human Cell N/A
    Human BMPR2-287H Recombinant Human BMPR2 Protein, GST-tagged Sf21 Insect Cell GST
    Human BMPR2-288H Recombinant Human BMPR2 Protein, GST-tagged Wheat Germ GST
    Human BMPR2-556H Recombinant Human BMPR2, Fc-tagged, Biotinylated Human Cell Fc
    Human BMPR2-577H Recombinant Human BMPR2 protein, His & T7-tagged E.coli His/T7
    Human BMPR2-868H Recombinant Human BMPR2 Protein, His-tagged HEK293 His
    Human BMPR2-870H Recombinant Human BMPR2 Protein, Fc/His-tagged HEK293 Fc/His
    Human BMPR2-993H Recombinant Human Bone Morphogenetic Protein Receptor, Type II, GST-tagged Sf9 Insect Cell His
    Mouse BMPR2-2440M Recombinant Mouse BMPR2 Protein Mammalian Cell His
    Rhesus Macaque BMPR2-549R Recombinant Rhesus monkey BMPR2 Protein, His-tagged Mammalian Cell His
    Chicken BMPR2-1108C Recombinant Chicken BMPR2 Mammalian Cell His

    bmpr2 involved in several pathways and played different roles in them. We selected most pathways bmpr2 participated on our site, such as Cytokine-cytokine receptor interaction, TGF-beta signaling pathway, Hippo signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with bmpr2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interaction IL18RAP; IL2RA; Il2; IL25; GM13305; IL1R1; CXCL2; GHRA; IL12BA; CXCL5
    TGF-beta signaling pathway ACVR1BA; RBL1; TGIF2; EP300; SMAD7; LEFTY1; ID2; GDF7; BMPR1BA; ACVR1
    Hippo signaling pathway WNT11; TGFBR2; FZD10; FRMD6; FGF1; BMP2; BMPR2; YWHAB; STK3; YAP1
    Signaling pathways regulating pluripotency of stem cells SOX2; WNT8B; HAND1; OTX1; BMPR1A; FGF2; FGFR4; WNT1; WNT7A; BMI1
    MicroRNAs in cancer TRP53; TGFB2; MET; CDC25B; ABCC1; TNC; CCNE2; HMOX1; TNXB; NOTCH2

    bmpr2 has several biochemical functions, for example, ATP binding, BMP binding, activin receptor activity, type II. Some of the functions are cooperated with other proteins, some of the functions could acted by bmpr2 itself. We selected most functions bmpr2 had, and list some proteins which have the same functions with bmpr2. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding BMPR1BB; ACTBL2; GSG2; CSNK1A1; ATP2A1; ATP6AP1; UBE2J1; SGK2; MYH13; MYO6
    BMP binding GREM1; CER1; TCAP; GDF5; BMPR2; HFE2; NBL1; GREM2
    activin receptor activity, type II BMPR2
    growth factor binding HTRA1A; HTRA1B; RPL37; OSMR; LIFR; GHRHR; SDCBP; FGFBP2; GHR; ERBB3
    metal ion binding ZNF394; DNLZ; SCNM1-PS; MOB4; ACACB; CAR7; ATP8B5; GALNT11; ZBTB16A; PDE3A
    protein binding USP6; FMNL3; NDUFAF3; KIAA0408; TWIST1; OXR1; ODF1; RAB38; SDCBP2; MED16
    receptor signaling protein serine/threonine kinase activity BMPR1B; ACVR1C; OXSR1B; ACVRL1; STK24B; SBK3; BMPR1A; TGFBR1; TGFB2; NEK4

    bmpr2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with bmpr2 here. Most of them are supplied by our site. Hope this information will be useful for your research of bmpr2.

    PRKG1; C4bpa; Prkcb; GDF5; MAPK8; Bmpr2; Ctbp1; Mos; Serpina3k; Lsp1; Cryab

    Guignabert, C; Dorfmuller, P; et al. Pathology and Pathobiology of Pulmonary Hypertension. SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE 34:551-559(2013).
    Yu, J; Taylor, L; et al. Altered expression and signal transduction of endothelin-1 receptors in heritable and idiopathic pulmonary arterial hypertension. JOURNAL OF CELLULAR PHYSIOLOGY 228:322-329(2013).

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