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Official Full Name caspase 6, apoptosis-related cysteine peptidase
Background This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms. [provided by RefSeq, Jul 2008]
Synonyms CASP6; caspase 6, apoptosis-related cysteine peptidase; MCH2; caspase-6; apoptotic protease MCH-2; caspase 6, apoptosis-related cysteine protease;
    • Species :
    • Bovine
    • Chicken
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CASP6-0426H Recombinant Human CASP6 Protein E.coli N/A
    Human CASP6-0427H Recombinant Human CASP6 Protein, GST-Tagged Wheat Germ GST
    Human CASP6-10735H Recombinant Human CASP6, GST-tagged E.coli GST
    Human CASP6-26830TH Recombinant Human CASP6 N/A
    Human CASP6-298H Recombinant Human CASP6 Protein, His-tagged E.coli His
    Human CASP6-568H Recombinant Human CASP6 Protein, His-tagged E.coli His
    Human CASP6-601H Recombinant Human Caspase 6, Apoptosis-related Cysteine Peptidase E.coli N/A
    Human CASP6-7834HCL Recombinant Human CASP6 293 Cell Lysate HEK293 N/A
    Mouse Casp6-16M Recombinant Mouse Casp6 protein, His-tagged E.coli His
    Mouse CASP6-2754M Recombinant Mouse CASP6 Protein Mammalian Cell His
    Bovine CASP6-566B Recombinant Bovine CASP6 Protein, His-tagged E.coli His
    Chicken CASP6-6291C Recombinant Chicken CASP6 Mammalian Cell His
    Zebrafish CASP6-2695Z Recombinant Zebrafish CASP6 Mammalian Cell His

    casp6 involved in several pathways and played different roles in them. We selected most pathways casp6 participated on our site, such as Apoptosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with casp6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    casp6 has several biochemical functions, for example, cysteine-type endopeptidase activity, cysteine-type endopeptidase activity involved in execution phase of apoptosis, cysteine-type peptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by casp6 itself. We selected most functions casp6 had, and list some proteins which have the same functions with casp6. You can find most of the proteins on our site.

    Function Related Protein
    cysteine-type endopeptidase activity ATG4D; CTSH; CTSJ; USP9X; USP42; DUB1; CASP7; PSD; CTSL.1; CTSM
    cysteine-type endopeptidase activity involved in execution phase of apoptosis CASP3B; CASP7; CASP3A; CASP6L1; CASP6; Casp3; CASP6L2
    cysteine-type peptidase activity FAM49BA; CAPN12; BLMH; Ctsl; CASP5; CTSW; ATG4A; CAPN1A; SOLH; USP12A
    identical protein binding BTK; CCT7; HOOK3; CLDN15; RNF4; DES; STK10; SDCBP; VPS41; SNCA
    protein binding ALKBH4; TTPA; ODF1; BBOX1; CACNA1SB; VIM; GDI2; DOK3; PWWP2B; FLRT3

    casp6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with casp6 here. Most of them are supplied by our site. Hope this information will be useful for your research of casp6.

    act-veid; NUCB2; NUCB1; PARP10; ATG16L1; APP; CASP3; SATB1; PRKAB2; CHD3; PIN1; TAB1; MAPK6; IKBKG

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