Recombinant Human CASP6
Cat.No. : | CASP6-26830TH |
Product Overview : | Recombinant full length Active Caspase 6 protein (Human) |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms. |
Biological activity : | SPECIFIC ACTIVITY: 13,000 units/mg |
Form : | Lyophilised:Reconstitute to 1 unit per μl in PBS containing 15% glycerol. Following reconstitution in PBS, the enzyme should be aliquoted and immediately stored at –80°C. |
Purity : | >95% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 15% Glycerol, PBS |
Storage : | Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles. |
Sequence Similarities : | Belongs to the peptidase C14A family. |
Gene Name : | CASP6 caspase 6, apoptosis-related cysteine peptidase [ Homo sapiens ] |
Official Symbol : | CASP6 |
Synonyms : | CASP6; caspase 6, apoptosis-related cysteine peptidase; caspase 6, apoptosis related cysteine protease; caspase-6; MCH2; |
Gene ID : | 839 |
mRNA Refseq : | NM_001226 |
Protein Refseq : | NP_001217 |
MIM : | 601532 |
Uniprot ID : | P55212 |
Chromosome Location : | 4q25 |
Pathway : | Apoptosis, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; Apoptosis, organism-specific biosystem; Apoptosis Modulation by HSP70, organism-specific biosystem; |
Function : | cysteine-type endopeptidase activity; cysteine-type peptidase activity; peptidase activity; protein binding; |
Products Types
◆ Recombinant Protein | ||
CASP6-0426H | Active Recombinant Human CASP6 Protein | +Inquiry |
CASP6-1245M | Recombinant Mouse CASP6 Protein, His (Fc)-Avi-tagged | +Inquiry |
CASP6-0427H | Recombinant Human CASP6 Protein, GST-Tagged | +Inquiry |
CASP6-566B | Recombinant Bovine CASP6 Protein, His-tagged | +Inquiry |
CASP6-568H | Recombinant Human CASP6 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
CASP6-7834HCL | Recombinant Human CASP6 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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