Recombinant Bovine CASP6 Protein, His-tagged

• Cat.No.: CASP6-566B
• Product Overview: Recombinant Bovine CASP6(Leu81~Asp179) fused with His tag at N-terminal was expressed in E. coli.

Specification

• Source: E. coli
• Species: Bovine
• Tag: His
• Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Molecular Mass: 12.8kDa
• Protein length: Leu81~Asp179
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
  If bio-activity of the protein is needed, please check active protein
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Reconstitution: Reconstitute in PBS or others

Gene Information

• Gene Name: CASP6 caspase 6 [ Bos taurus ]
• Official Symbol: CASP6
• Synonyms: CASP-6; caspase 6, apoptosis-related cysteine peptidase
• Gene ID: 538409
• mRNA Refseq: NM_001035419
• Protein Refseq: NP_001030496
• UniProt ID: Q3T0P5

Reviews

12/24/2022

Its remarkable performance in ELISA, protein electron microscopy structure analysis, and Western Blotting sets it apart as a top recommendation.

12/13/2018

The CASP6 protein has proven invaluable in protein electron microscopy structure analysis, allowing for detailed investigations and providing critical insights.

02/12/2018

Whether it's protein quantification, structural analysis, or Western Blotting, the CASP6 protein has consistently delivered exceptional results, earning my highest recommendation.

Q&As

Are there any potential therapeutic applications of targeting CASP6 in Alzheimer's disease?

Targeting CASP6 activity may offer a potential therapeutic strategy for slowing down the progression of Alzheimer's disease.

Can targeting CASP6 protein have applications beyond neurodegenerative diseases?

There is potential for CASP6 to be targeted in other diseases involving aberrant cell death pathways, such as certain types of cancer and autoimmune diseases.

Are there any specific drugs that target CASP6 protein?

Several research groups are working on developing small molecule inhibitors and other drugs that specifically target CASP6 for therapeutic purposes.

Are there any potential side effects of targeting CASP6 for therapeutic purposes?

As with any targeted therapy, potential side effects and off-target effects of CASP6 inhibition or modulation need to be carefully evaluated in clinical trials.

What other diseases are being studied in relation to CASP6 protein?

CASP6 is also being investigated in the context of other neurodegenerative disorders such as Parkinson's disease and amyotrophic lateral sclerosis (ALS).