CCL24

  • Official Full Name

    chemokine (C-C motif) ligand 24

  • Overview

    C-C motif chemokine 24 (CCL24), also known as Eotaxin-2 and MPIF-2, is a 119 amino acid secreted protein that is found in activated monocytes and activated T lymphocytes. After signal sequence processing and maturation, it becomes 93 amino acids long (27 to 119). CCL 24 belongs to the intercrine beta (chemokine CC) family and is N- glycosylated after post-translational modification. It serves as a chemotactic factor for resting T-lymphocytes, and eosinophils. CCL24 has a lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. It is a strong suppressor of colony formation by a multi-potential hematopoietic progenitor cell line. CCL24 binds to CCR3.
  • Synonyms

    Ckb-6; MPIF-2; MPIF2; SCYA24; C-C motif chemokine 24; CK-beta-6; eosinophil chemotactic protein 2; eotaxin-2; myeloid progenitor inhibitory factor 2; small inducible cytokine subfamily A (Cys-Cys), member 24; small-inducible cytokine A24;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • CHO
  • E.coli
  • HEK293
  • Human
  • In Vitro Cell Free System
  • Insect Cell
  • Insect Cells
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Biotin
  • C
  • His
  • Fc
  • GST
  • hFc
  • His (Fc)
  • Avi
  • N/A
  • N
  • Tag Free
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CCL24-102H Active Recombinant Human Chemokine (C-C motif) Ligand 24, MIgG2a Fc-tagged CHO Fc
Human CCL24-103H Active Recombinant Human Chemokine (C-C motif) Ligand 24, HIgG1 Fc-tagged CHO Fc
Human CCL24-036H Active Recombinant Human CCL24 Protein, hFc-tagged HEK293 hFc Val27-Cys119
Human CCL24-151H Active Recombinant Human CCL24 Protein, His-tagged HEK293 His Val27-Cys119
Human CCL24-128C Active Recombinant Human CCL24 Protein (78 aa) E.coli 78
Human CCL24-101H Recombinant Human CCL24 Protein (27-119), N-hFc tagged CHO N-hFc 27-119
Human CCL24-357H Recombinant Human Chemokine (C-C motif) Ligand 24 Human N/A
Human CCL24-138H Recombinant Human CCL24, Fc-tagged CHO Fc
Human CCL24-207H Recombinant Human CCL24 protein E.coli N/A 78
Human CCL24-035H Recombinant Human CCL24 Protein, His-tagged HEK293 His
Human CCL24-258H Recombinant Human CCL24 protein, His-tagged Insect Cells His Met1-Cys119
Human CCL24-816H Recombinant Human CCL24 protein, His-tagged E.coli His Val27~Cys119 (Accession # O00175)
Human CCL24-0629H Recombinant Human CCL24 Protein, GST-Tagged Wheat Germ GST
Human CCL24-437HCL Recombinant Human CCL24 cell lysate Insect Cell N/A
Human CCL24-65H Recombinant Human CCL24 Protein, Biotin-tagged E.coli Biotin
Human CCL24-2932HF Recombinant Full Length Human CCL24 Protein, GST-tagged In Vitro Cell Free System GST 119 amino acids
Human CCL24-51H Recombinant Human CCL24 Protein E.coli 78 amino acid
Human CCL24-1294H Recombinant Human CCL24 Protein (Val27-Cys119), C-His tagged Mammalian cells C-His Val27-Cys119
Human CCL24-0885H Recombinant Human CCL24 Protein (Val27-Cys119), His tagged E.coli His Val27-Cys119
Mouse Ccl24-475M Recombinant Mouse Ccl24 protein E.coli N/A 93
Mouse Ccl24-817M Recombinant Mouse Ccl24 protein, His-tagged E.coli His Val27~Val119 (Accession # Q9JKC0)
Mouse Ccl24-046C Active Recombinant Mouse Ccl24 Protein (93 aa) E.coli 93
Mouse Ccl24-151M Active Recombinant Mouse Ccl24 Protein E.coli
Mouse Ccl24-1348M Active Recombinant Mouse Ccl24 Protein E.coli Ile24-Val119
Mouse Ccl24-5452M Recombinant Mouse Ccl24 Protein (Val27-Val119) E.coli Tag Free Val27-Val119
Rat Ccl24-818R Recombinant Rat Ccl24 protein, His-tagged E.coli His Val27~Val119 (Accession # Q5PPP2)
Rat Ccl24-638R Recombinant Rat Ccl24 protein E.coli N/A 98
Rhesus Macaque CCL24-687R Recombinant Rhesus monkey CCL24 Protein, His-tagged Mammalian Cell His
Rhesus Macaque CCL24-515R-B Recombinant Rhesus Macaque CCL24 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque CCL24-515R Recombinant Rhesus Macaque CCL24 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

CCL24 involved in several pathways and played different roles in them. We selected most pathways CCL24 participated on our site, such as Cytokine-cytokine receptor interaction, Chemokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CCL24 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cytokine-cytokine receptor interactionM17;RNF207B;TNFRSF13C;CXCL11;FLT1;LEP;IL2RB;IFNA1;PDGFA
Chemokine signaling pathwayRAF1;CXCL12;PLCB2;PTK2B;RHOA;CXCL9;CCR8;GM10591;CXCR5

CCL24 has several biochemical functions, for example, CCR chemokine receptor binding, chemokine activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CCL24 itself. We selected most functions CCL24 had, and list some proteins which have the same functions with CCL24. You can find most of the proteins on our site.

Function Related Protein
CCR chemokine receptor bindingCCL15;CCL13;CCL18;CCL3L1;CCL19;CCL24;CCL14;CCL35.1;CCL20
chemokine activityCcl12;CCL25B;CCL6;CCL34A.4;CKLF;CXCL10;CXCL14;CCL34B.4;CXCL9

CCL24 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CCL24 here. Most of them are supplied by our site. Hope this information will be useful for your research of CCL24.

Gene Family

Chemokines Cytokines

Research Area

Related articles

Makita, N; Hizukuri, Y; et al. IL-10 enhances the phenotype of M2 macrophages induced by IL-4 and confers the ability to increase eosinophil migration. INTERNATIONAL IMMUNOLOGY 27:131-141(2015).
Huang, XS; Gruner, B; et al. Distinctive cytokine, chemokine, and antibody responses in Echinococcus multilocularis-infected patients with cured, stable, or progressive disease. MEDICAL MICROBIOLOGY AND IMMUNOLOGY 203:185-193(2014).
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