• Official Full Name

    chemokine (C-C motif) ligand 24

  • Background

    C-C motif chemokine 24 (CCL24), also known as Eotaxin-2 and MPIF-2, is a 119 amino acid secreted protein that is found in activated monocytes and activated T lymphocytes. After signal sequence processing and maturation, it becomes 93 amino acids long (27 to 119). CCL 24 belongs to the intercrine beta (chemokine CC) family and is N- glycosylated after post-translational modification. It serves as a chemotactic factor for resting T-lymphocytes, and eosinophils. CCL24 has a lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. It is a strong suppressor of colony formation by a multi-potential hematopoietic progenitor cell line. CCL24 binds to CCR3.
  • Synonyms

    Ckb-6; MPIF-2; MPIF2; SCYA24; C-C motif chemokine 24; CK-beta-6; eosinophil chemotactic protein 2; eotaxin-2; myeloid progenitor inhibitory factor 2; small inducible cytokine subfamily A (Cys-Cys), member 24; small-inducible cytokine A24;
    • Type:
    • Recombinant Proteins
    • Cell & Tissue Lysates
    • Protein Pre-coupled Magnetic Beads
    • Species :
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • CHO
    • E. coli
    • E.coli
    • HEK293
    • Human
    • Insect Cell
    • Insect Cells
    • Mammalian Cell
    • Mammalian cells
    • Wheat Germ
    • Tag :
    • Biotin
    • C
    • His
    • Fc
    • GST
    • hFc
    • His (Fc)
    • Avi
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CCL24-258H Recombinant Human CCL24 protein, His-tagged Insect Cells His
    Human CCL24-101H Active Recombinant Human Chemokine (C-C motif) Ligand 24, HIgG1 Fc-tagged, mutant CHO Fc
    Human CCL24-437HCL Recombinant Human CCL24 cell lysate Insect Cell N/A
    Human CCL24-138H Recombinant Human CCL24, Fc-tagged CHO Fc
    Human CCL24-816H Recombinant Human CCL24 protein, His-tagged E.coli His
    Human CCL24-102H Active Recombinant Human Chemokine (C-C motif) Ligand 24, MIgG2a Fc-tagged CHO Fc
    Human CCL24-357H Recombinant Human Chemokine (C-C motif) Ligand 24 Human N/A
    Human CCL24-103H Active Recombinant Human Chemokine (C-C motif) Ligand 24, HIgG1 Fc-tagged CHO Fc
    Human CCL24-0629H Recombinant Human CCL24 Protein, GST-Tagged Wheat Germ GST
    Human CCL24-65H Recombinant Human CCL24 Protein, Biotin-tagged E.coli Biotin
    Human CCL24-035H Recombinant Human CCL24 Protein, His-tagged HEK293 His
    Human CCL24-151H Active Recombinant Human CCL24 Protein, His-tagged HEK293 His
    Human CCL24-036H Active Recombinant Human CCL24 Protein, hFc-tagged HEK293 hFc
    Human CCL24-51H Recombinant Human CCL24 Protein E.coli
    Human CCL24-1294H Recombinant Human CCL24 Protein (Val27-Cys119), C-His tagged Mammalian cells C-His
    Human CCL24-0885H Recombinant Human CCL24 Protein (Val27-Cys119), His tagged E.coli His
    Human CCL24-207H Recombinant Human CCL24 protein E.coli N/A
    Human CCL24-128C Recombinant Human CCL24 Protein (78 aa) E.coli
    Mouse Ccl24-151M Recombinant Mouse Ccl24 Protein E.coli
    Mouse Ccl24-1348M Recombinant Mouse Ccl24 Protein E. coli
    Mouse Ccl24-817M Recombinant Mouse Ccl24 protein, His-tagged E.coli His
    Mouse Ccl24-046C Recombinant Mouse Ccl24 Protein (93 aa) E.coli
    Mouse Ccl24-475M Recombinant Mouse Ccl24 protein E.coli N/A
    Rat Ccl24-818R Recombinant Rat Ccl24 protein, His-tagged E.coli His
    Rat Ccl24-638R Recombinant Rat Ccl24 protein E.coli N/A
    Rhesus Macaque CCL24-687R Recombinant Rhesus monkey CCL24 Protein, His-tagged Mammalian Cell His
    Rhesus Macaque CCL24-515R-B Recombinant Rhesus Macaque CCL24 Protein Pre-coupled Magnetic Beads HEK293
    Rhesus Macaque CCL24-515R Recombinant Rhesus Macaque CCL24 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    • Involved Pathway
    • Protein Function
    • Interacting Protein
    • CCL24 Related Articles
    • CCL24 Related Gene Family
    • CCL24 Related Research Area

    CCL24 involved in several pathways and played different roles in them. We selected most pathways CCL24 participated on our site, such as Cytokine-cytokine receptor interaction, Chemokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CCL24 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interactionBMP2;CXCR4A;BMP7A;CRFB4;IL26;IL8L1;CXCR1;RELT;IL10RB
    Chemokine signaling pathwayHCK;CCL6;CCR1;SHC4;NCF1;GNG12;GRK4;CXCL10;ADRBK1

    CCL24 has several biochemical functions, for example, CCR chemokine receptor binding, chemokine activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CCL24 itself. We selected most functions CCL24 had, and list some proteins which have the same functions with CCL24. You can find most of the proteins on our site.

    Function Related Protein
    CCR chemokine receptor bindingCCL20A.3;CCL19A.2;CCL20;CCL34B.4;CCL17;CCL16;CCL22;CCL33.3;CCL38.1
    chemokine activityAMCF-II;CXCL6;CCL38A.5;CCL34B.1;XCL2;CCL19;CCL25;CCL21B;CXCL13

    CCL24 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CCL24 here. Most of them are supplied by our site. Hope this information will be useful for your research of CCL24.

    Makita, N; Hizukuri, Y; et al. IL-10 enhances the phenotype of M2 macrophages induced by IL-4 and confers the ability to increase eosinophil migration. INTERNATIONAL IMMUNOLOGY 27:131-141(2015).
    Huang, XS; Gruner, B; et al. Distinctive cytokine, chemokine, and antibody responses in Echinococcus multilocularis-infected patients with cured, stable, or progressive disease. MEDICAL MICROBIOLOGY AND IMMUNOLOGY 203:185-193(2014).
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