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Ccl6

Official Full Name

chemokine (C-C motif) ligand 6
Overview

This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted;proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two;adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity on resting T lymphocytes and;monocytes, lower activity on neutrophils and no activity on activated T lymphocytes. The protein is also a strong;suppressor of colony formation by a multipotential hematopoietic progenitor cell line. In addition, the product of;this gene is a potent agonist at CC chemokine receptor 1. Two alternatively spliced variants encoding different active;isoforms have been identified.
Synonyms

CCL6; chemokine (C-C motif) ligand 6; C-C motif chemokine 6; C10; CCL 6; Chemokine C C motif Ligand 6; Chemokine C-C motif Ligand 6; MRP1; SCYA6; Small Inducible Cytokine A6; CC chemokine C10; small-inducible cytokine A6; MRP-1;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Mouse
Rat

Source

E.coli
HEK293
Human Cell
Mammalian Cell

Tag

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Mouse	CCL6-8449M	Active Recombinant Mouse CCL6	E.coli	Non		Inquiry
Mouse	Ccl6-617M	Recombinant Mouse Ccl6 protein	E.coli	Non	95	Inquiry
Mouse	Ccl6-3993M	Recombinant Mouse Ccl6 protein, His-tagged	HEK293	His	Gly22-Ala116	$623 / 10 µg
Mouse	Ccl6-34M	Recombinant Mouse Chemokine (C-C Motif)Ligand 6	E.coli	Non		Inquiry
Mouse	Ccl6-1448M	Recombinant Mouse Ccl6 protein, His & T7-tagged	E.coli	His&T7	Gly22~Ala116 (Accession # P27784)	Inquiry
Mouse	CCL6-1896MCL	Recombinant Mouse CCL6 cell lysate	Human Cell	Non		Inquiry
Mouse	Ccl6-134M	Active Recombinant Mouse Ccl6 Protein	E.coli			Inquiry
Mouse	CCL6-480M	Recombinant Mouse CCL6 Protein			116	Inquiry
Rat	CCL6-1215R	Recombinant Rat CCL6 Protein	Mammalian Cell	His		Inquiry
Rat	CCL6-1156R	Recombinant Rat CCL6 protein	E.coli	Non	94	Inquiry
Rat	Ccl6-1449R	Recombinant Rat Ccl6 protein, His & T7-tagged	E.coli	His&T7	Ala21~Ala115 (Accession # Q68FP3)	Inquiry
Rat	CCL6-873R-B	Recombinant Rat CCL6 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	CCL6-873R	Recombinant Rat CCL6 Protein, His (Fc)-Avi-tagged	HEK293	His&Fc&Avi		Inquiry

Involved Pathway
Protein Function
Interacting Protein
Other Resource

Ccl6 involved in several pathways and played different roles in them. We selected most pathways Ccl6 participated on our site, such as Cytokine-cytokine receptor interaction, Chemokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Ccl6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Cytokine-cytokine receptor interaction	BMPR1AA;IL1R2;IFNA7;IFNPHI3;PDGFC;CCL1;CRFB4;PRL;TNFSF15
Chemokine signaling pathway	CXCL9;GNG2;PRKCB;CCL20;NFKB1;ROCK2;VAV3;CDC42;CXCL8

Ccl6 has several biochemical functions, for example, chemokine activity, cytokine activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Ccl6 itself. We selected most functions Ccl6 had, and list some proteins which have the same functions with Ccl6. You can find most of the proteins on our site.

Function	Related Protein
chemokine activity	CCL27B;CCL34A.4;CX3CL1;CXCL2;CCL4;CCL8;CCL33.2;CXCL1;CCL44
cytokine activity	IL36RN;LTA;INHA;IL20;IFNPHI1;CCL38.1;Il2;IL12BA;IFNA10

Ccl6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Ccl6 here. Most of them are supplied by our site. Hope this information will be useful for your research of Ccl6.