|Official Full Name||chemokine (C-C motif) ligand 6|
|Background||This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted;proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two;adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity on resting T lymphocytes and;monocytes, lower activity on neutrophils and no activity on activated T lymphocytes. The protein is also a strong;suppressor of colony formation by a multipotential hematopoietic progenitor cell line. In addition, the product of;this gene is a potent agonist at CC chemokine receptor 1. Two alternatively spliced variants encoding different active;isoforms have been identified.|
|Synonyms||CCL6; chemokine (C-C motif) ligand 6; C-C motif chemokine 6; C10; CCL 6; Chemokine C C motif Ligand 6; Chemokine C-C motif Ligand 6; MRP1; SCYA6; Small Inducible Cytokine A6; CC chemokine C10; small-inducible cytokine A6; MRP-1|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
Ccl6 involved in several pathways and played different roles in them. We selected most pathways Ccl6 participated on our site, such as Cytokine-cytokine receptor interaction, Chemokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Ccl6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Cytokine-cytokine receptor interaction||IL17A; CCL26; CCR1L1; IL1R1; CXCR4A; FLT3; CCL21B; IFNA12; Il23a; Il12b; FLT3LG|
|Chemokine signaling pathway||IKBKB; CCL16; CCL28; CCL17; GNG4; VAV3; SHC4; RHOA; CCL20; CCL25|
Ccl6 has several biochemical functions, for example, chemokine activity, cytokine activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Ccl6 itself. We selected most functions Ccl6 had, and list some proteins which have the same functions with Ccl6. You can find most of the proteins on our site.
|chemokine activity||CCL34B.4; CCL17; CCL34B.9; CCL15; CXCL12; CCL5; CXCL1; CCL3; CXCL20; CCL38A.5|
|cytokine activity||TGFB3; TNFSF13B; TNFSF9; WNT1; HMGB1A; GDF1; IFNA2; BMP4; GDF15; IL1A|
Ccl6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Ccl6 here. Most of them are supplied by our site. Hope this information will be useful for your research of Ccl6.