• Official Full Name

    chemokine (C-C motif) receptor-like 2

  • Overview

    This gene encodes a chemokine receptor like protein, which is predicted to be a seven transmembrane protein and most closely related to CCR1. Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. This gene is expressed at high levels in primary neutrophils and primary monocytes, and is further upregulated on neutrophil activation and during monocyte to macrophage differentiation. The function of this gene is unknown. This gene is mapped to the region where the chemokine receptor gene cluster is located.
  • Synonyms

    CCRL2; chemokine (C-C motif) receptor-like 2; C-C chemokine receptor-like 2; CKRX; CRAM A; CRAM B; HCR; Chemokine (C-C motif) receptor like 2; Chemokine receptor CCR11; Chemokine receptor X; CRAMA; CRAMB; FLJ55815; MGC116710; MGC34104; Putative MCP 1 chemokine receptor; OTTHUMP00000209758; OTTHUMP00000209759; putative MCP-1 chemokine receptor; CRAM; CRAM-A; CRAM-B;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Assay Kits
  • Bos taurus (Bovine)
  • Homo sapiens (Human)
  • Human
  • Macaca mulatta (Rhesus macaque)
  • Mouse
  • Mus musculus (Mouse)
  • Sus scrofa (Pig)
  • E.coli expression system
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CCRL2-15H Recombinant Human CCRL2 protein Wheat Germ N/A
Human CCRL2-16H Recombinant Human CCRL2 protein, GST-tagged Wheat Germ GST
Human CCRL2-311HCL Recombinant Human CCRL2 cell lysate HEK293 Flag
Human CCRL2-312HCL Recombinant Human CCRL2 cell lysate HEK293 N/A
Human CCRL2-653HF Recombinant Full Length Human CCRL2 Protein In Vitro Cell Free System
Mouse CCRL2-3020M Recombinant Mouse CCRL2 Protein Mammalian Cell His
Mouse CCRL2-1425M Recombinant Mouse CCRL2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse CCRL2-1425M-B Recombinant Mouse CCRL2 Protein Pre-coupled Magnetic Beads HEK293
Bos taurus (Bovine) RFL13466BF Recombinant Full Length Bovine Chemokine C-C Motif Receptor-Like 2(Ccrl2) Protein, His-Tagged E.coli expression system His
Homo sapiens (Human) RFL27336HF Recombinant Full Length Human C-C Chemokine Receptor-Like 2(Ccrl2) Protein, His-Tagged E.coli expression system His
Macaca mulatta (Rhesus macaque) RFL4908MF Recombinant Full Length Macaca Mulatta C-C Chemokine Receptor-Like 2(Ccrl2) Protein, His-Tagged E.coli expression system His
Mus musculus (Mouse) RFL26212MF Recombinant Full Length Mouse C-C Chemokine Receptor-Like 2(Ccrl2) Protein, His-Tagged E.coli expression system His
Sus scrofa (Pig) RFL13601SF Recombinant Full Length Pig Chemokine C-C Motif Receptor-Like 2(Ccrl2) Protein, His-Tagged E.coli expression system His
Kit-1164 CCRL2 CHO-K1 β-Arrestin Orphan GPCR Assay Kit N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • CCRL2 Related Research Area

CCRL2 involved in several pathways and played different roles in them. We selected most pathways CCRL2 participated on our site, such as Chemokine receptors bind chemokines, Class A/1 (Rhodopsin-like receptors), GPCR ligand binding, which may be useful for your reference. Also, other proteins which involved in the same pathway with CCRL2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Chemokine receptors bind chemokinesCXCR7B;CCL35.2;CCR7;CCR9;CX3CR1;CCR1;CCR3;CXCR6;CCR5
Class A/1 (Rhodopsin-like receptors)ADRA1D;S1PR1;OPN4B;ADRA2A;CCL35.1;GPR31B;CCL35.2;PPY;OPN1LW2
GPCRs, Class A Rhodopsin-likeCNR1;GPR171;OPN4;GPR20;GPR75;GPR63;CCBP2;OPN1MW;GPR65
Peptide ligand-binding receptorsEDNRAB;PYY;HCRT;TAC3;PROK1;PENKB;NMBB;PROK2;INSL3

CCRL2 has several biochemical functions, for example, CCR chemokine receptor binding, chemokine receptor activity, chemokine receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CCRL2 itself. We selected most functions CCRL2 had, and list some proteins which have the same functions with CCRL2. You can find most of the proteins on our site.

Function Related Protein
CCR chemokine receptor bindingCCL14;CX3CL1;CCL19A.2;CCL20B;CCL35.1;XCL2;CXCL32B.1;XCL1;CCL19A.1
chemokine receptor activityGPR17;CXCR3;CXCR7B;CCR6A;CCBP2;CCR6;CCR1L1;CCR9A;CMKLR1
chemokine receptor bindingCCRL2;CCL21B;Ccl21a;CCL5;CCL19;Ccl21c;S100A14;CCL25;XCL1

CCRL2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CCRL2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CCRL2.

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