"CCRL2" Related Products

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Recombinant Human CCRL2 protein, GST-tagged

Cat.No.: CCRL2-16H
Product Overview: Recombinant Human CCRL2(49 a.a. - 344 a.a.) fused with GST tag at N-terminal was expressed in Wheat Germ.
Description: This gene encodes a chemokine receptor like protein, which is predicted to be a seven transmembrane protein and most closely related to CCR1. Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. This gene is expressed at high levels in primary neutrophils and primary monocytes, and is further upregulated on neutrophil activation and during monocyte to macrophage differentiation. The function of this gene is unknown. This gene is mapped to the region where the chemokine receptor gene cluster is located.
Source: Wheat Germ
Species: Human
Tag: GST
Form: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Molecular Mass: 58.3 kDa
AA Sequence: FVIGVLDNLLVVLILVKYKGLKRAENIYLLNLAVSNLCFLLTLPFWAHAGGDPMCKILIGLYFVGLYSETFFNCL LTVQRYLVFLHKGNFFSARRRVPCGIITSVLAWVTAILATLPEYVVYKPQMEDQKYKCAFSRTPFLPADETFWKH FLTLKMNISVLVLPLFIFTFLYVQMRKTLRFREQRYSLFKLVFAIMVVFLLMWAPYNIAFFLSTFKEHFSLSDCK SSYNLDKSVHITKLIATTHCCINPLLYAFLDGTFSKYLCRCFHLRSNTPLQPRGQSAQGTSREEPDHSTEV
Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
Notes: Best use within three months from the date of receipt of this protein.
Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Gene Name: CCRL2 chemokine (C-C motif) receptor-like 2 [ Homo sapiens ]
Official Symbol: CCRL2
Synonyms: CCRL2; chemokine (C-C motif) receptor-like 2; C-C chemokine receptor-like 2; CKRX; CRAM A; CRAM B; HCR; chemokine receptor X; chemokine receptor CCR11; putative MCP-1 chemokine receptor; CRAM; CRAM-A; CRAM-B; FLJ55815; MGC34104; MGC116710;
Gene ID: 9034
mRNA Refseq: NM_001130910
Protein Refseq: NP_001124382
MIM: 608379
UniProt ID: O00421
Chromosome Location: 3p21
Pathway: GPCRs, Class A Rhodopsin-like, organism-specific biosystem;
Function: CCR chemokine receptor binding; G-protein coupled receptor activity; chemokine receptor activity; chemokine receptor binding; receptor activity; signal transducer activity;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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