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CCT2

  • Official Full Name

    chaperonin containing TCP1, subunit 2 (beta)

  • Overview

    CCT2 is one of eight largely unrelated subunit proteins found in a protein chaperone complex known as the chaperonin-containing TCP-1 (CCT) or TRiC complex. The CCT complex is an abundanct cytoslic component that is credited with helping newly synthesized
  • Synonyms

    CCT2; chaperonin containing TCP1, subunit 2 (beta); T-complex protein 1 subunit beta; Cctb; T-complex protein 1, beta subunit; chaperonin containing t-complex polypeptide 1, subunit 2; chaperonin containing t-complex polypeptide 1, beta subunit; 99D;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • Yeast
  • GST
  • His
  • His (Fc)
  • Avi
  • SUMO
  • MYC
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CCT2-0709H Recombinant Human CCT2 Protein, GST-Tagged Wheat Germ GST
Human CCT2-27951TH Recombinant Human CCT2, His-tagged E.coli His
Human CCT2-7691HCL Recombinant Human CCT2 293 Cell Lysate HEK293 N/A
Human CCT2-1463H Recombinant Human CCT2 Protein (Met1-Met488), His tagged E.coli His Met1-Met488
Human CCT2-2657H Recombinant Human CCT2 protein, His-SUMO-tagged E.coli His-SUMO 2-535aa
Human CCT2-3040HF Recombinant Full Length Human CCT2 Protein, GST-tagged In Vitro Cell Free System GST 535 amino acids
Human CCT2-1742H Recombinant Human CCT2 Protein (2-535 aa), His-tagged Yeast His 2-535 aa
Mouse CCT2-3023M Recombinant Mouse CCT2 Protein Mammalian Cell His
Mouse CCT2-1426M Recombinant Mouse CCT2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse CCT2-1426M-B Recombinant Mouse CCT2 Protein Pre-coupled Magnetic Beads HEK293
Mouse Cct2-802M Recombinant Mouse Cct2 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Rat CCT2-1231R Recombinant Rat CCT2 Protein Mammalian Cell His
Rat CCT2-889R Recombinant Rat CCT2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat CCT2-889R-B Recombinant Rat CCT2 Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey CCT2-382C Recombinant Cynomolgus CCT2 Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey CCT2-130C-B Recombinant Cynomolgus Monkey CCT2 Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey CCT2-130C Recombinant Cynomolgus Monkey CCT2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque CCT2-713R Recombinant Rhesus monkey CCT2 Protein, His-tagged Mammalian Cell His
Rhesus Macaque CCT2-540R-B Recombinant Rhesus Macaque CCT2 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque CCT2-540R Recombinant Rhesus Macaque CCT2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish CCT2-11501Z Recombinant Zebrafish CCT2 Mammalian Cell His
Chicken CCT2-1907C Recombinant Chicken CCT2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

CCT2 involved in several pathways and played different roles in them. We selected most pathways CCT2 participated on our site, such as Assembly of the primary cilium, Association of TriC/CCT with target proteins during biosynthesis, BBSome-mediated cargo-targeting to cilium, which may be useful for your reference. Also, other proteins which involved in the same pathway with CCT2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Assembly of the primary ciliumBBS1;BBS13;NDE1;TCTN3;IFT20;TRAF3IP1;EXOC6;MKS1;WDR34
Association of TriC/CCT with target proteins during biosynthesisTCP1;CCT8;FBXL5;CCT3;CCT7;KIFC3;FBXW5;CCT6A;NOP56
BBSome-mediated cargo-targeting to ciliumCCT3;BBS7;TCP1;LZTFL1;CCT8;TTC8;SSTR3;SETD6;BBS2
Cargo trafficking to the periciliary membranePKD1;BBS1;SSTR3;ARL3;BBS4;BBS7;BBS5;EXOC5;EXOC8
Chaperonin-mediated protein foldingCCT5;TUBB4B;CCT6A;CCT4;PFDN1;FBXW5;CCT8;PFDN6;TUBB4A
Cooperation of Prefoldin and TriC/CCT in actin and tubulin foldingTUBB4B;PFDN4;CCT7;PFDN2;TUBA3D;PFDN1;TCP1;VBP1;PFDN6
Folding of actin by CCT/TriCCCT8;CCT4;CCT2;TCP1;CCT5;CCT7;CCT6A;CCT3
Formation of tubulin folding intermediates by CCT/TriCCCT6A;CCT3;TUBA3D;CCT4;CCT2;TCP1;TUBB4B;CCT7;TUBB4A

CCT2 has several biochemical functions, for example, ATP binding, protein binding, ubiquitin protein ligase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CCT2 itself. We selected most functions CCT2 had, and list some proteins which have the same functions with CCT2. You can find most of the proteins on our site.

Function Related Protein
ATP bindingABCG2D;DNAJA1;NME3;MLKL;MYLK4;ABCG2A;HELLS;DCLK2;ACTA1
protein bindingSYNM;MAP3K1;SUV39H1;HELLS;MYEF2;OSTB;NOL6;RIPK1;SNAPIN
ubiquitin protein ligase bindingUBE2K;SLC25A5;RIPK1;MAGEA2;UBE2U;RNF34;UBE2B;TRAF3;USP13
unfolded protein bindingCRYAA;TTC1;CRYABA;H2-KE2;TRAP1;PPIB;HSPA1B;SIL1;CLN3

CCT2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CCT2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CCT2.

PPP2CA; PPP4C; PPP2CB; STRN3; BBS7; WRAP53

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