CCT2

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CCT2

Official Full Name chaperonin containing TCP1, subunit 2 (beta)
Background CCT2 is one of eight largely unrelated subunit proteins found in a protein chaperone complex known as the chaperonin-containing TCP-1 (CCT) or TRiC complex. The CCT complex is an abundanct cytoslic component that is credited with helping newly synthesized
Synonyms CCT2; chaperonin containing TCP1, subunit 2 (beta); T-complex protein 1 subunit beta; Cctb; T-complex protein 1, beta subunit; chaperonin containing t-complex polypeptide 1, subunit 2; chaperonin containing t-complex polypeptide 1, beta subunit; 99D
    • Species :
    • Chicken
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Yeast
    • Tag :
    • GST
    • His
    • MYC/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CCT2-0709H Recombinant Human CCT2 Protein, GST-Tagged Wheat Germ GST
    Human CCT2-1742H Recombinant Human CCT2 Protein (2-535 aa), His-tagged Yeast His
    Human CCT2-27951TH Recombinant Human CCT2, His-tagged E.coli His
    Human CCT2-7691HCL Recombinant Human CCT2 293 Cell Lysate HEK293 N/A
    Mouse CCT2-3023M Recombinant Mouse CCT2 Protein Mammalian Cell His
    Mouse Cct2-802M Recombinant Mouse Cct2 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Rat CCT2-1231R Recombinant Rat CCT2 Protein Mammalian Cell His
    Cynomolgus Monkey CCT2-382C Recombinant Cynomolgus CCT2 Protein, His-tagged Mammalian Cell His
    Rhesus Macaque CCT2-713R Recombinant Rhesus monkey CCT2 Protein, His-tagged Mammalian Cell His
    Chicken CCT2-1907C Recombinant Chicken CCT2 Mammalian Cell His
    Zebrafish CCT2-11501Z Recombinant Zebrafish CCT2 Mammalian Cell His

    CCT2 involved in several pathways and played different roles in them. We selected most pathways CCT2 participated on our site, such as Assembly of the primary cilium, Association of TriC/CCT with target proteins during biosynthesis, BBSome-mediated cargo-targeting to cilium, which may be useful for your reference. Also, other proteins which involved in the same pathway with CCT2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Assembly of the primary cilium IFT172; EXOC1; DYNC1I2; ARL13B; BBS2; ARL3; MARK4; TCTEX1D1; WDR19; CEP135
    Association of TriC/CCT with target proteins during biosynthesis FBXW9; CCT4; FBXL5; CCT2; NOP56; CCT3; FBXW4; CCT8; KIFC3; FBXW2
    BBSome-mediated cargo-targeting to cilium RAB3IP; BBS12; CCT3; TCP1; CCT5; PROL1; BBS4; BBS1; SSTR3; CCT8
    Cargo trafficking to the periciliary membrane SETD6; BBS7; BBS4; CCT5; CCT2; CNGA2; UNC119B; PROL1; RHOL; BBS1
    Chaperonin-mediated protein folding FBXW9; KIFC3; FBXW5; NOP56; FBXW2; TUBA1B; FBXL5; CCT4; CCT8; PFDN1
    Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding CCT6A; PFDN5; TUBB4B; CCT5; TCP1; CCT7; PFDN2; CCT4; TUBA3D; VBP1
    Folding of actin by CCT/TriC CCT4; CCT3; CCT5; CCT8; TCP1; CCT6A; CCT2; CCT7
    Formation of tubulin folding intermediates by CCT/TriC CCT5; CCT4; TUBB4A; TCP1; CCT3; CCT7; CCT6A; TUBA1B; CCT2; TUBA3D

    CCT2 has several biochemical functions, for example, ATP binding, protein binding, ubiquitin protein ligase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CCT2 itself. We selected most functions CCT2 had, and list some proteins which have the same functions with CCT2. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding AURKC; ATP2A2; PL10; DDX54; ABCG2B; HYOU1; HARS; LACE1; ATP1A1A.4; RPS6KA3
    protein binding NANOS2; STX3; FGFBP1; RSPO1; RAN; NSL1; FXYD6; EFHC2; MORF4L1; HOMEZ
    ubiquitin protein ligase binding BAG4; SUMO1; STUB1; WASH1; MOAP1; GPR37; VCL; RIPK1; PRDX6; USP13
    unfolded protein binding CCT6A; CALR3; CCT5; SCG5; AIPL1; PFDN5; NPM1; DNAJA4; CCT2; CLN3

    CCT2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CCT2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CCT2.

    PPP2CA; PPP4C; PPP2CB; STRN3; BBS7; WRAP53

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