CD177

  • Official Full Name

    CD177 Molecule

  • Overview

    CD177 antigen is a protein that in humans is encoded by the CD177 gene. NB1, a glycosyl-phosphatidylinositol (GPI)-linked N-glycosylated cell surface glycoprotein, was first described in a case of neonatal alloimmune neutropenia (Lalezari et al., 1971. [supplied by OMIM].
  • Synonyms

    CD177 antigen; PRV-1; HNA-2a; NB1 GP; CD177; NB1 glycoprotein; cell surface receptor; polycythemia rubra vera 1; Human neutrophil alloantigen 2a; NB1; PRV1; HNA2A; Polycythemia rubra vera protein 1; CD177 molecule; UNQ595/PRO1181;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • E.coli
  • HEK293
  • HEK293T
  • Human Cell
  • Human cells
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • C
  • His
  • DYKDDDDK
  • Fc
  • Flag
  • GST
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
  • T7|His
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CD177-320H Active Recombinant Human CD177, His-tagged Mammalian cells His
Human CD177-248H Recombinant Human CD177, Fc-tagged Human Cell Fc
Human CD177-0730H Recombinant Human CD177 Protein, GST-Tagged Wheat Germ GST
Human CD177-7807H Recombinant Human CD177 protein, His-tagged HEK293 His
Human CD177-63H Recombinant Human CD177 protein, T7/His-tagged E.coli T7/His
Human CD177-125H Recombinant Human CD177, His tagged Human Cell His
Human CD177-778HCL Recombinant Human CD177 cell lysate Human Cell N/A
Human CD177-4896H Recombinant Human CD177 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human CD177-3041H Recombinant Human CD177 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human CD177-962HFL Recombinant Full Length Human CD177 Protein, C-Flag-tagged Mammalian cells Flag
Human CD177-151H Recombinant Human CD177 Protein, DYKDDDDK-tagged Human cells DYKDDDDK
Human CD177-0912H Recombinant Human CD177 Protein (Cys133-Ser301), N-His tagged E.coli N-His
Human CD177-2990HF Recombinant Full Length Human CD177 Protein, GST-tagged In Vitro Cell Free System GST
Human CD177-513H Recombinant Human CD177 protein, His-GST-tagged E.coli His/GST
Human CD177-126H Recombinant Human CD177 Protein, His-tagged HEK293 His
Human CD177-533H Recombinant Human CD177 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human CD177-533H-B Recombinant Human CD177 Protein Pre-coupled Magnetic Beads HEK293
Human CD177-5035H Recombinant Human CD177 Protein (Met1-Gly407), C-His tagged Mammalian cells C-His
Mouse CD177-3040M Recombinant Mouse CD177 Protein Mammalian Cell His
Mouse Cd177-5651M Recombinant Mouse Cd177 protein, His & T7-tagged E.coli His/T7
Mouse CD177-1437M Recombinant Mouse CD177 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse CD177-1437M-B Recombinant Mouse CD177 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • CD177 Related Articles
  • CD177 Related Research Area

CD177 involved in several pathways and played different roles in them. We selected most pathways CD177 participated on our site, such as Cell surface interactions at the vascular wall, Common Pathway of Fibrin Clot Formation, Formation of Fibrin Clot (Clotting Cascade), which may be useful for your reference. Also, other proteins which involved in the same pathway with CD177 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cell surface interactions at the vascular wallSLC7A10;GRB7;SLC16A8;CEACAM1;SLC3A2B;PROCR;FCER1GL;SIRPA;GRB14
Common Pathway of Fibrin Clot FormationCFHL3;CFHL4;PROCR;CFHL2;PROCA;SERPINE2;SERPINA1L;CFHL1;F13A1B
Formation of Fibrin Clot (Clotting Cascade)PROCR;PRTN3;PROCA;F13A1B;CD177;CFHL2;F3A;LOC100514666;F3B
HemostasisCFHL2;KIF3C;KIF15;CFHL3;ZFPM1;SLC7A6;HBB-BH1;DOCK6;DOCK9

CD177 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CD177 itself. We selected most functions CD177 had, and list some proteins which have the same functions with CD177. You can find most of the proteins on our site.

Function Related Protein
protein bindingKCNJ9;CIB3;RAMP3;MGARP;CCL18;KRTAP10-4;TCL1A;CLCNKB;PAWR

CD177 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD177 here. Most of them are supplied by our site. Hope this information will be useful for your research of CD177.

KCNIP3; EWSR1

Shahabi, V; Berman, D; et al. Gene expression profiling of whole blood in ipilimumab-treated patients for identification of potential biomarkers of immune-related gastrointestinal adverse events. JOURNAL OF TRANSLATIONAL MEDICINE 11:-(2013).
Tamarozzi, MB; Soares, SG; et al. Comparative analysis of the pathological events involved in immune and non-immune TRALI models. VOX SANGUINIS 103:309-321(2012).
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