Recombinant Cynomolgus CDH3 Protein, His Tagged

• Cat.No.: CDH3-11246C
• Product Overview: Cynomolgus Cadherin-3 Protein, His Tag is expressed from human 293 cells (HEK293). It contains AA Asp 108-Gly 654 (Accession # A0A2K5WPN9). This protein carries a polyhistidine tag at the C-terminus. Predicted N-terminus: Asp 108

Specification

• Species: Cynomolgus
• Source: HEK293
• Tag: His
• Protein Length: 108-654 aa
• Description: Cadherin-3 （also known as P-cadherin）is a classical cell-to-cell adhesion molecule with a homeostatic function in several normal tissues. In humans, cadherin-3 is only detected in a few organs. However, its overexpression is strongly associated with a poor prognosis in some solid tumors including breast, lung and pancreatic cancers.
• Form: Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
• Molecular Mass: The protein has a calculated MW of 61.9 kDa. The protein migrates as 70-85 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Endotoxin: Less than 1.0 EU/μg by the LAL method/rFC method.
• Purity: >90% as determined by SDS-PAGE.
• Storage: This product is stable after storage at: -20 to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 μg/μL. Centrifuge the vial at 4 centigrade before opening to recover the entire contents.

Gene Information

• Gene Name: CDH3 cadherin 3 [ Macaca fascicularis (crab-eating macaque) ]
• Official Symbol: CDH3
• Synonyms: CDH3; cadherin 3; cadherin-3; cadherin 3, type 1, P-cadherin (placental)
• Gene ID: 102142204
• mRNA Refseq: XM_005592358
• Protein Refseq: XP_005592415
• UniProt ID: A0A2K5WPN9