CLIC2 Protein


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Official Full Name chloride intracellular channel 2
Background Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 2 is a member of the p64 family; the protein is detected in fetal liver and adult skeletal muscle tissue.This gene maps to the candidate region on chromosome X for incontinentia pigmenti.
Synonyms CLIC2; chloride intracellular channel 2; chloride intracellular channel protein 2; XAP121; CLIC 2b; CLIC2_HUMAN; CLIC2b; OTTHUMP00000196471; XAP 121; OTTHUMP00000024248
    • Species :
    • Chicken
    • Homo sapiens (Human)
    • Human
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • E.coli expression system
    • HEK293
    • HEK293T
    • In Vitro Cell Free System
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CLIC2-1478H Recombinant Human CLIC2 Protein, GST-tagged Wheat Germ GST
    Human CLIC2-27815TH Recombinant Human CLIC2, His-tagged E.coli His
    Human CLIC2-27817TH Recombinant Human CLIC2 N/A
    Human CLIC2-3512H Recombinant Human Chloride Intracellular Channel 2, His-tagged E.coli His
    Rat CLIC2-1449R Recombinant Rat CLIC2 Protein Mammalian Cell His
    Rhesus Macaque CLIC2-909R Recombinant Rhesus monkey CLIC2 Protein, His-tagged Mammalian Cell His
    Chicken CLIC2-2786C Recombinant Chicken CLIC2 Mammalian Cell His
    Zebrafish CLIC2-682Z Recombinant Zebrafish CLIC2 Mammalian Cell His
    Human CLIC2-7447HCL Recombinant Human CLIC2 293 Cell Lysate HEK293 N/A
    Human CLIC2-2179HF Recombinant Full Length Human CLIC2 Protein, GST-tagged In Vitro Cell Free System GST
    Homo sapiens (Human) RFL35635HF Recombinant Full Length Human Chloride Intracellular Channel Protein 2(Clic2) Protein, His-Tagged E.coli expression system His
    Human CLIC2-3907H Recombinant Human CLIC2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK

    CLIC2 involved in several pathways and played different roles in them. We selected most pathways CLIC2 participated on our site, such as Ion channel transport, Stimuli-sensing channels, Transmembrane transport of small molecules, which may be useful for your reference. Also, other proteins which involved in the same pathway with CLIC2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Ion channel transport CLCN5; TSC22D3; TRPM1B; ASPH; Ano3; ATP13A5; FXYD6; GABRR2A; SLC9B2; MCOLN2
    Stimuli-sensing channels ANO7; SLC17A3; TRPC4; ANO4; SLC9A10; ANO8; ANO6; TRPM6; TRPA1A; CLCA1
    Transmembrane transport of small molecules SLC7A10; SLC35A2; AQP3B; SLC43A1A; SLC35A3A; SLC43A2B; SLC9B2; ATP2B1B; SLC39A3; ABCA8

    CLIC2 has several biochemical functions, for example, chloride channel activity, glutathione peroxidase activity, NOT glutathione transferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CLIC2 itself. We selected most functions CLIC2 had, and list some proteins which have the same functions with CLIC2. You can find most of the proteins on our site.

    Function Related Protein
    chloride channel activity SLC26A7; CLCA1; GABRA1; TTYH2L; GABRG2; BEST1; SLC26A3; SLC26A1; TTYH3B; ANO2
    glutathione peroxidase activity GPX3; GPX4A; MGST1; GSTT1; GPX4B; GPX7; GPX4; GPX1B; MGST3; MGST2
    NOT glutathione transferase activity CLIC2; ALOX5AP; CLIC1; CLIC5; CLIC3
    protein binding TNFAIP8L2; PPP2R5C; KCTD6; SEC14L4; TRIM38; MYOC; UXT; KIF6; SENP6; PPP2R3A
    voltage-gated ion channel activity KCNF1A; TPC3; SCN8AA; KCNS3A; CACNA1DA; KCNG4A; KCNK10; CACNA1C; KCNS3B; CALHM1

    CLIC2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CLIC2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CLIC2.


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