|Official Full Name||collagen, type III, alpha 1|
|Background||This gene encodes the pro-alpha1 chains of type III collagen, a fibrillar collagen that is found in extensible connective tissues such as skin, lung, uterus, intestine and the vascular system, frequently in association with type I collagen. Mutations in this gene are associated with Ehlers-Danlos syndrome types IV, and with aortic and arterial aneurysms. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008]|
|Synonyms||COL3A1; collagen, type III, alpha 1; EDS4A; collagen alpha-1(III) chain; collagen, fetal; alpha1 (III) collagen; Ehlers-Danlos syndrome type IV, autosomal dominant;|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
COL3A1 involved in several pathways and played different roles in them. We selected most pathways COL3A1 participated on our site, such as Amoebiasis, Assembly of collagen fibrils and other multimeric structures, Binding and Uptake of Ligands by Scavenger Receptors, which may be useful for your reference. Also, other proteins which involved in the same pathway with COL3A1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Amoebiasis||PIK3CD; CSF2; IL-8; COL1A1; IFNG; VCL; GM-CSF; LAMC3; COL4A4; SERPINB2|
|Assembly of collagen fibrils and other multimeric structures||CTSL1; COL6A1; BMP1; CTSL2; COL4A3; COL11A1B; COL10A1A; LOXL3; COL1A2; MMP13|
|Binding and Uptake of Ligands by Scavenger Receptors||IGLC2; STAB2; HPX; AMBP; APOA1B; Alb; SCGB3A2; COL1A2; HYOU1; HP|
|Collagen biosynthesis and modifying enzymes||COL10A1; COL5A3A; COL9A1B; COL1A1; PCOLCE; COL25A1; P3H2; COL4A5; COL4A3; COL28A1D|
|Collagen formation||LEPREL1; CRTAP; COL23A1; TLL1; MMP20; COL10A1A; LOXL2; COL16A1; COL4A4; LEPREL2|
|ECM-receptor interaction||ITGA6; TNC; COL6A3; ITGA10; GP5; COL27A1; COMP; TNXB; SPP1; CD36|
|Endothelins||EDNRA; EDN3; EDN2; EDN1; COL3A1; EDNRB; COL1A2; CYSLTR1|
|Extracellular matrix organization||BGNA; LEPREL1; COL28A1; DMP1; CTSG; COL6A3; MFAP3; COL6A2; MGC174155; COL5A3A|
COL3A1 has several biochemical functions, for example, SMAD binding, extracellular matrix structural constituent, integrin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by COL3A1 itself. We selected most functions COL3A1 had, and list some proteins which have the same functions with COL3A1. You can find most of the proteins on our site.
|SMAD binding||SKI; MAGI2; TGFBRAP1; SKOR1B; COL5A2; SMAD2; BMPR1A; HIPK2; ACVR1; BMP2|
|extracellular matrix structural constituent||ELN; PRELP; COL11A1A; FBN1; LAMB1; LAMC1; OPTC; LAMA1; MATN3; COL1A1A|
|integrin binding||FBLN1; PPAP2B; ICAM3; ITGA6; IGF1; EMP2; EGFL6; WISP1; SFRP2; MMP14|
|metal ion binding||ZDHHC16B; RAG1; CTDSPL; ZNF664; GLRX5; GUCA1E; PHF2; C1GALT1B; ZNF559; SDHDA|
|platelet-derived growth factor binding||PDGFA; PDGFB; PDGFRB; PDGFRA; COL6A1; COL1A2; COL5A1; COL4A1; COL3A1; COL2A1|
|protein binding||ZNF350; MYH8; HEXIM1; CACYBP; PARD6A; SCARB1; TMIGD2; DHH; MDFI; DCUN1D4|
COL3A1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with COL3A1 here. Most of them are supplied by our site. Hope this information will be useful for your research of COL3A1.
all3_aedae; zwf; LOX; ispH; lcrS; pdpD2; q5nfa1_fratt; galT; pbpG; htrE; nagE; opuD; mutTA; thiF; katB; rpoB; q81vw1_bacan; q8ckb2_yerpe; mutY