Recombinant Human COL3A1

• Cat.No.: COL3A1-28012TH
• Product Overview: Recombinant Full-length Human Collagen-III : the human proalpha1 (III) and both alpha and beta subunits of prolyl hydroxylase were co-expressed in the yeast Pichia pastoris. Procollagen III was converted into mature collagen by a controlled proteinase dig

Specification

• Species: Human
• Tag: Non
• Description: This gene encodes the pro-alpha1 chains of type III collagen, a fibrillar collagen that is found in extensible connective tissues such as skin, lung, uterus, intestine and the vascular system, frequently in association with type I collagen. Mutations in this gene are associated with Ehlers-Danlos syndrome types IV, and with aortic and arterial aneurysms. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Storage buffer: Component: 10mM HClPreservatives: none.
• Storage: Store at +4°C.

Gene Information

• Gene Name: COL3A1 collagen, type III, alpha 1 [ Homo sapiens ]
• Official Symbol: COL3A1
• Synonyms: COL3A1; collagen, type III, alpha 1; EDS4A, Ehlers Danlos syndrome type IV, autosomal dominant; collagen alpha-1(III) chain
• Gene ID: 1281
• mRNA Refseq: NM_000090
• Protein Refseq: NP_000081
• MIM: 120180
• Uniprot ID: P02461
• Chromosome Location: 2q32.2
• Pathway: Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Axon guidance, organism-specific biosystem; Developmental Biology, organism-specific biosystem; ECM-receptor interaction, organism-specific biosystem
• Function: SMAD binding; extracellular matrix structural constituent; integrin binding; integrin binding; platelet-derived growth factor binding