Recombinant Human COL3A1 protein, His & GST-tagged

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Recombinant Human COL3A1 protein, His & GST-tagged

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Cat.No. : COL3A1-7927H
Product Overview : Recombinant Human COL3A1 aa. (Gly1059~Leu1466 (Accession # P02461)) fused with N-terminal His & GST tag was produced in E. coli cells.
Description : This gene encodes the pro-alpha1 chains of type III collagen, a fibrillar collagen that is found in extensible connective tissues such as skin, lung, uterus, intestine and the vascular system, frequently in association with type I collagen. Mutations in this gene are associated with Ehlers-Danlos syndrome types IV, and with aortic and arterial aneurysms. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.
Source : E. coli
Species : Human
Tag : His & GST
Form : Freeze-dried powder
Molecular Mass : 68 kDa as determined by SDS-PAGE reducing conditions.
Protein length : Gly1059~Leu1466 (Accession # P02461)
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : >95%
Characteristic : The isoelectric point is 6.6.
Applications : SDS-PAGE; WB; ELISA; IP
Stability : The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage Buffer : Supplied as liquid form in Phosphate buffered saline(PBS), pH 7.4.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4.
Gene Name : COL3A1 collagen type III alpha 1 chain [ Homo sapiens (human) ]
Official Symbol : COL3A1
Synonyms : COL3A1; collagen type III alpha 1 chain; EDS4A; collagen alpha-1(III) chain; Ehlers-Danlos syndrome type IV, autosomal dominant; alpha-1 type III collagen; alpha1 (III) collagen; collagen, fetal; collagen, type III, alpha 1
Gene ID : 1281
mRNA Refseq : NM_000090.3
Protein Refseq : NP_000081.1
UniProt ID : P02461
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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