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Native Human COL3A1 Protein

Cat.No. : COL3A1-001H
Product Overview : Native human Collagen Type III has been prepared from human placenta and is chromatographically and immunologically pure. This product is free from other collagens, human serum proteins and non-collagen extracellular matrix proteins. This product reacts with Anti-Collagen Type III.
  • Specification
  • Gene Information
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Description : This gene encodes the pro-alpha1 chains of type III collagen, a fibrillar collagen that is found in extensible connective tissues such as skin, lung, uterus, intestine and the vascular system, frequently in association with type I collagen. Mutations in this gene are associated with Ehlers-Danlos syndrome types IV, and with aortic and arterial aneurysms. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.
Source : Human Placenta
Species : Human
Form : Liquid (sterile filtered)
Applications : ELISA: 1:10,000
Western Blot: 1:1000
Immunohistochemistry: 1:100-1:500
ImmunoPrecipitation: 1:100-1:500
Other Dilution: User Optimized
Storage : Store vial at 4 centigrade prior to opening. This product is stable at 4 centigrade as an undiluted liquid. Dilute only prior to immediate use.
Concentration : 1.0 mg/ml by modified Lowry assay
Storage Buffer : 0.5 M Acetic Acid
Preservative : 0.01% (w/v) Sodium Azide
Gene Name : COL3A1 collagen type III alpha 1 chain [ Homo sapiens (human) ]
Official Symbol : COL3A1
Synonyms : COL3A1; collagen type III alpha 1 chain; EDS4A; EDSVASC; PMGEDSV; collagen alpha-1(III) chain; Ehlers-Danlos syndrome type IV, autosomal; dominant; alpha-1 type III collagen; alpha1 (III) collagen; collagen, fetal; collagen, type III, alpha 1
Gene ID : 1281
mRNA Refseq : NM_000090
Protein Refseq : NP_000081
MIM : 120180
UniProt ID : P02461

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How can the study of COL3A1 protein aid in the development of personalized medicine for vEDS patients? 04/12/2023

Understanding the specific genetic and protein alterations in vEDS patients can help tailor individualized treatment strategies based on the patient's unique molecular profile.

Can COL3A1 protein analysis be used for prenatal screening of vEDS? 07/05/2022

Yes, analysis of COL3A1 protein levels in prenatal samples may provide valuable information for assessing the risk of vEDS in the developing fetus.

How can the measurement of COL3A1 protein levels aid in the early detection of vEDS? 03/28/2021

Elevated or decreased levels of COL3A1 protein may serve as potential biomarkers for early detection and risk assessment of vEDS, especially in at-risk individuals or families.

What are the current challenges in the clinical application of COL3A1 protein analysis? 01/08/2020

Challenges include the need for standardized assays and reference ranges for COL3A1 protein levels, as well as the interpretation of results in the context of individual patient variability.

Can the measurement of COL3A1 protein levels be used to monitor disease progression in vEDS patients? 12/31/2019

Yes, monitoring changes in COL3A1 protein levels may provide insights into disease progression and response to treatment in vEDS patients.

Customer Reviews (3)

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Reviews
01/23/2020

    This protein demonstrates great performance in WB assays, providing accurate and reliable results that are crucial for protein analysis.

    05/08/2019

      The COL3A1 protein is of exceptional quality, making it an ideal choice to meet my experimental needs.

      07/27/2016

        the COL3A1 protein has proven to be an invaluable tool in protein electron microscopy (EM) structure analysis.

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