|Official Full Name||cytokine receptor-like factor 2|
|Background||The protein encoded by this gene is a receptor for thymic stromal lymphopoietin (TSLP). Together with the interleukin 7 receptor (IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Two transcript variants encoding different isoforms have been found for this gene.|
|Synonyms||CRLF2; cytokine receptor-like factor 2; CRL2; TSLPR; IL-XR; TSLP receptor; P2RY8/CRLF2 fusion; cytokine receptor-like 2; cytokine receptor CRL2 precusor; thymic stromal lymphopoietin receptor; thymic stromal lymphopoietin protein receptor; thymic stromal-|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
CRLF2 involved in several pathways and played different roles in them. We selected most pathways CRLF2 participated on our site, such as Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CRLF2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Cytokine-cytokine receptor interaction||IFNA17; BMPR1AB; IL29; TNFRSF9A; TGFBR2; ACVR2B; LIFRA; CCL20B; PPBP; VEGFB|
|Jak-STAT signaling pathway||IFNB; GM-CSF; HRASA; PIK3CG; IL2RGB; TP-1; CCND2; IL5; SOCS6B; CSH2|
CRLF2 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by CRLF2 itself. We selected most functions CRLF2 had, and list some proteins which have the same functions with CRLF2. You can find most of the proteins on our site.
CRLF2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CRLF2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CRLF2.