|Official Full Name||E2F transcription factor 1|
|Background||The E2F transcription factors are essential for regulation of the cell cycle. Physiological E2F is a heterodimer composed of an E2F subunit together with a DP subunit. Six members of the E2F family have been identified, and each E2F subunit has a DNA bind|
|Synonyms||E2F1; E2F transcription factor 1; RBBP3; transcription factor E2F1; RBP3; PBR3; RBAP-1; RBBP-3; PRB-binding protein E2F-1; retinoblastoma-binding protein 3; retinoblastoma-associated protein 1; E2F-1; RBAP1|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
e2f1 involved in several pathways and played different roles in them. We selected most pathways e2f1 participated on our site, such as Activation of BH3-only proteins, Activation of NOXA and translocation to mitochondria, Activation of PUMA and translocation to mitochondria, which may be useful for your reference. Also, other proteins which involved in the same pathway with e2f1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Activation of BH3-only proteins||AKT3; DYNLL2; E2F1; CDK5RAP2; BCL2L11; YWHAQ|
|Activation of NOXA and translocation to mitochondria||E2F1|
|Activation of PUMA and translocation to mitochondria||E2F1|
|Adipogenesis||CISD1; EPAS1B; MEF2AA; MEF2B; CREB1; EGR2B; RORAA; GADD45A; CEBPB; E2F1|
|Apoptosis||IL1RAP; DIABLO; DBNLB; PIK3R2; AKT2; GZMF; PLEC; TICAM1; CASP2; CASP10|
|Assembly of the pre-replicative complex||MCM8; GMNN; CDT1; E2F2; E2F1; E2F3|
|Association of licensing factors with the pre-replicative complex||E2F2; E2F3; CDT1; E2F1; GMNN|
|Bladder cancer||CDK4; MMP2; MAP2K2; E2F1; HBEGF; ARAF; MAPK3; TYMP; MDM2; SRC|
e2f1 has several biochemical functions, for example, DNA binding, core promoter binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by e2f1 itself. We selected most functions e2f1 had, and list some proteins which have the same functions with e2f1. You can find most of the proteins on our site.
|DNA binding||ASCL4; TRIM26; ZNF74; TRP63; RBM5; HES1; RCOR1; FOXF2A; ZBTB1; ZNF230|
|core promoter binding||ELK4; MTF1; GATA1; AGO2; INSM1B; EZH2; ARNTL; MYOG; MED1; REST|
|protein binding||ANKRD49; SHANK3; LCORL; IGFBP2; HIST1H3F; SCIMP; TXNL4B; TNS3; CRYBA2; PLP2|
|protein kinase binding||CHEK2; FGF19; SFN; SNAP91; ACTA2; FAM83D; MAPK4; CCNL2; RPS3; CLTC|
|sequence-specific DNA binding||HOXC12B; IRX4; CREMB; NOTCH1; FOXN2B; RAX2; TFCP2L1; PPARAB; FOXN1; ZNF148|
|transcription factor activity, sequence-specific DNA binding||DMRT2; MTA1; ESR2; TFAP2B; HOXB7; TBX22; NR2F2; TFAM; ATF3; PURBA|
|transcription factor binding||RB1; IFT172; CAMTA2; ARHGEF2; HDAC5; MED25; AIP; HES3; FOSB; CEBPA|
e2f1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with e2f1 here. Most of them are supplied by our site. Hope this information will be useful for your research of e2f1.