fcgr1a

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fcgr1a

Official Full Name Fc fragment of IgG, high affinity Ia, receptor (CD64)
Background CD64 is the high-affinity IgG Fc receptor belonging to the immunoglobulin supergene family (Guyre, 2002). CD64 is a 72 kDa glycoprotein which binds monomeric IgG (human IgG1>IgG3>>IgG4>>>IgG2 and mouse IgG3>IgG2a>>>IgG1, IgG2b). Three genes: FcgammaR1A, FcgammaR1B and FcgammaR1C, which have >98 percent identity at the nucleotide level, have been identified and mapped to chromosome 1, band q21.1 (Sun,1997)). The FcgammaR1A gene, which specified the high-affinity IgG receptor, encodes three C2-type Ig-like extracellular domains, a 21 amino acid transmembrane region, and a charge cytoplasmic tail of 61 amino acids (Sun, 1997)(van de Winkel,1993).
Synonyms FCGR1A; Fc fragment of IgG, high affinity Ia, receptor (CD64); high affinity immunoglobulin gamma Fc receptor I; Fc receptor, IgG, high affinity I; high affinity IgG Fc receptor, subunit beta; Fc fragment of IgG high affinity Ib receptor; high-affinity immunoglobulin gamma Fc receptor I; Fc fragment of IgG, high affinity Ib, receptor for (CD64); Fcgr1; Fcgr1b; FcgammaRI
    • Species :
    • Cynomolgus
    • Cynomolgus Monkey
    • Human
    • Rabbit
    • Rat
    • Rhesus monkey
    • Source :
    • E.coli
    • HEK293
    • Human
    • Human Cell
    • Human cells
    • Mouse
    • Wheat Germ
    • Tag :
    • Avi
    • His
    • DYKDDDDK
    • Fc
    • GST
    • His-Avi
    • mIgG1
    • mIgG2a
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human FCGR1A-151H Recombinant Human FCGR1A Protein, DYKDDDDK-tagged Human cells DYKDDDDK
    Human FCGR1-2562HCL Recombinant Human FCGR1 cell lysate Human Cell N/A
    Human FCGR1A-12818H Recombinant Human FCGR1A, His-tagged E.coli His
    Human FCGR1A-179H Recombinant Human FCGR1A, His-tagged HEK293 His
    Human FCGR1A-180H Recombinant Human FCGR1A, His-tagged, Biotinylated HEK293 His
    Human FCGR1A-2224H Recombinant Human FCGR1A, His tagged Human Cell His
    Human FCGR1A-27573H Recombinant Human FCGR1A Protein, GST-tagged Wheat Germ GST
    Human FCGR1A-27573TH Recombinant Human FCGR1A, Fc-tagged Wheat Germ Fc
    Human FCGR1A-373H Recombinant Human FCGR1A Protein, His & Avi-tagged, Biotinylated HEK293 His/Avi
    Human FCGR1A-3817H Recombinant Human FCGR1A Protein, Avi/His-tagged, biotinylated HEK293 Avi/His
    Human FCGR1A-3818H Recombinant Human Fc Fragment Of IgG, High Affinity Ia, Receptor (CD64), AVI-tagged Human His
    Human FCGR1A-381H Recombinant Human FCGR1A protein, His-Avi-tagged HEK293 His-Avi
    Human FCGR1A-3987H Recombinant Human FCGR1A Protein Wheat Germ N/A
    Human FCGR1A-3988H Recombinant Human FCGR1A Protein, GST-tagged Wheat Germ GST
    Human FCGR1A-6279HCL Recombinant Human FCGR1A 293 Cell Lysate HEK293 N/A
    Human FCGR1A-7166H Recombinant Human Fc Fragment Of IgG, High Affinity Ia, Receptor (CD64), His-tagged E.coli His
    Rat CAB11539MR Mouse Anti-Rat CD64 Monoclonal Antibody Mouse N/A
    Rat FCGR1-1972RCL Recombinant Rat FCGR1 cell lysate Human Cell N/A
    Rat Fcgr1a-4081R Recombinant Rat Fcgr1a, His tagged Human Cell His
    Cynomolgus Monkey FCGR1A-01C Recombinant Cynomolgus Monkey FCGR1A Protein, His-tagged HEK293 His
    Cynomolgus FCGR1A-3818C Recombinant Cynomolgus FCGR1A protein, His-Avi-tagged, Biotinylated HEK293 His/Avi
    Rhesus monkey FCGR1A-1798R Recombinant Rhesus Monkey FCGR1A Protein HEK293 N/A
    Rhesus monkey FCGR1A-1799R Recombinant Rhesus Monkey FCGR1A Protein, mIgG1-tagged HEK293 mIgG1
    Rhesus monkey FCGR1A-1800R Recombinant Rhesus Monkey FCGR1A Protein, mIgG2a-tagged HEK293 mIgG2a
    Rabbit FCGR1A-904R Recombinant Rabbit FCGR1A Protein (Met1-Phe291), His-tagged HEK293 His

    fcgr1a involved in several pathways and played different roles in them. We selected most pathways fcgr1a participated on our site, such as Phagosome, Osteoclast differentiation, Hematopoietic cell lineage, which may be useful for your reference. Also, other proteins which involved in the same pathway with fcgr1a were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Phagosome LAMP2; ATP6V1C1B; SCARB1; ATP6V0A1A; CTSLA; ATP6AP1; H2-AB1; RAC1; ACTB; RAB7
    Osteoclast differentiation STAT1; LILRB3; IKBKB; LILRA1; SIRPB1; LILRA4; FCGR4; MAPK3; TREM2; NOX3
    Hematopoietic cell lineage IL5; GP9; ITGB3; FCGR1A; CD33; CD3E; ITGA2; CD2; FCER2; CD1E
    Fc gamma R-mediated phagocytosis ARPC5L; ASAP3; PRKCA; WASF3; PIP5K1A; RAC2; PIK3CD; LIMK1; WASF2; PIK3CG
    Leishmaniasis TLR4; MAPK13; IL1B; HLA-DQB1; IL1A; MAPK11; IFNGR1; HLA-DMB; TGFB1; HLA-DQA2
    Staphylococcus aureus infection ITGAM; FPR3; DSG1A; MBL1; HLA-DPA1; FCGR2B; HLA-DOA; C2; SELPLG; FPR2
    Tuberculosis TLR1; LAMP1; IL12B; IFNA7; CD209C; FCGR4; Il23a; TGFB3; CAMK2D; CAMK2A
    Transcriptional misregulation in cancer MEF2C; HOXA11; MEN1; LYL1; RXRA; HIST1H3E; ELK4; HDAC1; SIX4; TMPRSS2
    Systemic lupus erythematosus GM14476; C1QB; HIST1H2AF; H2AFB3; H2AFY; HIST1H4N; CD86; HIST1H2AJ; H2AFB1; GM14478

    fcgr1a has several biochemical functions, for example, IgG binding, protein binding, receptor signaling protein activity. Some of the functions are cooperated with other proteins, some of the functions could acted by fcgr1a itself. We selected most functions fcgr1a had, and list some proteins which have the same functions with fcgr1a. You can find most of the proteins on our site.

    Function Related Protein
    IgG binding PIP; FCGR1B; UMOD; FCGR1A; FCGRT; FCGR3A; cgr2b; FCGR2C; FCGR1; FCGR2B
    protein binding NOTCH4; SF3A1; PEX3; ACY3; SCYL3; ACE; CEP164; CELSR1; PTPLAD1; IL32
    receptor signaling protein activity ADRB1; PLCG1; DOK1; SMAD1; ADCYAP1; FCGR1A; TRAIP; RGS12B; FLRT1; FLRT3

    fcgr1a has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with fcgr1a here. Most of them are supplied by our site. Hope this information will be useful for your research of fcgr1a.

    FCGR3A; SYK; hldE; CBL; SHC1; LCP2

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