fgf19

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fgf19

Official Full Name fibroblast growth factor 19
Background The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumor growth and invasion. This growth factor is a high affinity, heparin dependent ligand for FGFR4. Expression of this gene was detected only in fetal but not adult brain tissue. Synergistic interaction of the chick homolog and Wnt-8c has been shown to be required for initiation of inner ear development. [provided by RefSeq, Jul 2008]
Synonyms FGF19; fibroblast growth factor 19; FGF-19;
    • Species :
    • Chicken
    • Human
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • Fc
    • Flag
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human FGF19-48H Recombinant Human FGF19 Protein, His-tagged HEK293 His
    Human FGF19-100H Recombinant Human Fibroblast Growth Factor 19, His-tagged E.coli His
    Human FGF19-132H Recombinant Human FGF19 Protein, His-tagged E.coli His
    Human FGF19-238H Recombinant Human FGF19 protein E.coli N/A
    Human FGF19-251H Recombinant Human FGF19, FLAG-tagged HEK293 Flag
    Human FGF19-252H Recombinant Human FGF19, Fc-tagged HEK293 Fc
    Human FGF19-27597TH Recombinant Human FGF19 E.coli N/A
    Human FGF19-27599TH Recombinant Human FGF19, His-tagged E.coli His
    Human FGF19-28824TH Recombinant Human FGF19 Protein, Fc-tagged E.coli Fc
    Human FGF19-4109H Recombinant Human FGF19 Protein, GST-tagged Wheat Germ GST
    Human FGF19-6244HCL Recombinant Human FGF19 293 Cell Lysate HEK293 N/A
    Human FGF19-7336H Recombinant Human FGF19, None tagged E.coli N/A
    Rat Fgf19-1815R Recombinant Rat Fgf19 protein, His-tagged E.coli His
    Chicken FGF19-6240C Recombinant Chicken FGF19 Mammalian Cell His
    Zebrafish FGF19-2002Z Recombinant Zebrafish FGF19 Mammalian Cell His

    fgf19 involved in several pathways and played different roles in them. We selected most pathways fgf19 participated on our site, such as MAPK signaling pathway, Ras signaling pathway, Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with fgf19 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    MAPK signaling pathway RELB; TGFB3; ARR3A; MAPK8IP3; DUSP16; PRKACG; NTRK1; FOS; CACNA1G; TGFB1A
    Ras signaling pathway FGF14; INS2; RASSF5; KLK1B4; HTR7; ABL1; PLA2G2F; MAPK3; PIK3R1; PLA2G12B
    Rap signaling pathway PLCB4; RASSF5; PRKD1; CALM4; PIK3R3; BRAF; RAP1GAP; FGFR1; KLK1B4; FGF12
    PIK-Akt signaling pathway BCL2L1; COL4A1; FGF1; PPP2CB; IL2RA; ITGA6; FGF10; Fgf15; STK11; LAMA1
    Regulation of actin cytoskeleton Itga10&Itgb1; PTK2; FGF6; FGF16; RAC1; CHRM5A; HRASB; ITGA2B; CDC42; BRK1
    Pathways in cancer RBX1; GNAQ; GNG10; MAP2K2; TPM3; LAMC2; PDGFRB; RAC1; HIF1A; PDGFRA
    Melanoma MAPK1; FGF1; MAP2K2; AKT1; RB1; FGF5; PIK3R1; FGF12; MAP2K1; FGF20

    fgf19 has several biochemical functions, for example, protein binding, protein kinase binding, protein phosphatase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by fgf19 itself. We selected most functions fgf19 had, and list some proteins which have the same functions with fgf19. You can find most of the proteins on our site.

    Function Related Protein
    protein binding ODF2; SERPINB9; TMEM182; MCRS1; URI1; ILF3; C1QTNF9; PLCB4; ATM; C5orf24
    protein kinase binding MAVS; HSPB1; DNAJC3; JTB; MS4A2; ADCY6; TBL2; RELA; CCNL2; HDAC7
    protein phosphatase binding TRAF3; RPA3; STAT3; HSP90B1; FLT4; CDKN1B; ITGA1; PPP6R1; TRP53; PPARG

    fgf19 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with fgf19 here. Most of them are supplied by our site. Hope this information will be useful for your research of fgf19.

    Walters, JRF; et al. Bile acid diarrhoea and FGF19: new views on diagnosis, pathogenesis and therapy. NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY 11:426-434(2014).
    Kong, B; Guo, GL; et al. Soluble Expression of Disulfide Bond Containing Proteins FGF15 and FGF19 in the Cytoplasm of Escherichia coli. PLOS ONE 9:-(2014).

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