• Official Full Name

    fibroblast growth factor 19

  • Background

    The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumor growth and invasion. This growth factor is a high affinity, heparin dependent ligand for FGFR4. Expression of this gene was detected only in fetal but not adult brain tissue. Synergistic interaction of the chick homolog and Wnt-8c has been shown to be required for initiation of inner ear development. [provided by RefSeq, Jul 2008]
  • Synonyms

    FGF19; fibroblast growth factor 19; FGF-19;
    • Type:
    • Recombinant Proteins
    • Cell & Tissue Lysates
    • Protein Pre-coupled Magnetic Beads
    • Species :
    • Chicken
    • Human
    • Rat
    • Zebrafish
    • Source :
    • E. coli
    • E.coli
    • HEK293
    • HEK293T
    • In Vitro Cell Free System
    • Mammalian Cell
    • Mammalian cells
    • Wheat Germ
    • Tag :
    • Fc
    • Flag
    • GST
    • His
    • His (Fc)
    • Avi
    • His(C
    • ter)
    • Myc
    • DDK
    • N/A
    • N
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Chicken FGF19-6240C Recombinant Chicken FGF19 Mammalian Cell His
    Human FGF19-7336H Recombinant Human FGF19, None tagged E.coli N/A
    Human FGF19-27599TH Recombinant Human FGF19, His-tagged E.coli His
    Human FGF19-3206H Recombinant Human FGF19 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human FGF19-27597TH Recombinant Human FGF19 E.coli N/A
    Human FGF19-132H Recombinant Human FGF19 Protein, His-tagged E.coli His
    Human FGF19-4109H Recombinant Human FGF19 Protein, GST-tagged Wheat Germ GST
    Human FGF19-3970H Recombinant Human FGF19 protein, His-tagged E.coli His
    Human FGF19-6244HCL Recombinant Human FGF19 293 Cell Lysate HEK293 N/A
    Human FGF19-4819HF Recombinant Full Length Human FGF19 Protein, GST-tagged In Vitro Cell Free System GST
    Human FGF19-032H Recombinant Human FGF19 Protein E. coli
    Human FGF19-1485H Recombinant Human FGF19 Protein, His-tagged E.coli N-His
    Human FGF19-252H Recombinant Human FGF19, Fc-tagged HEK293 Fc
    Human FGF19-121F Recombinant Human FGF19 Protein (195 aa) E.coli
    Human FGF19-906H Recombinant Human FGF19 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Human FGF19-75H Recombinant Active Human FGF19 Protein, His-tagged(C-ter) E.coli His(C-ter)
    Human FGF19-251H Recombinant Human FGF19, FLAG-tagged HEK293 Flag
    Human FGF19-906H-B Recombinant Human FGF19 Protein Pre-coupled Magnetic Beads HEK293
    Human FGF19-238H Recombinant Human FGF19 protein E.coli N/A
    Human FGF19-857HFL Recombinant Full Length Human FGF19 Protein, C-Flag-tagged Mammalian cells Flag
    Human FGF19-100H Recombinant Human Fibroblast Growth Factor 19, His-tagged E.coli His
    Human FGF19-28824TH Recombinant Human FGF19 Protein, Fc-tagged E.coli Fc
    Human FGF19-48H Recombinant Human FGF19 Protein, His-tagged HEK293 His
    Human FGF19-5231H Recombinant Human FGF19 protein, GST-tagged E.coli GST
    Human FGF19-1484H Recombinant Human FGF19 Protein, His-tagged E.coli N-His
    Human FGF19-01H Recombinant Human FGF-19 Protein, His-Tagged HEK293 His
    Rat Fgf19-1815R Recombinant Rat Fgf19 protein, His-tagged E.coli His
    Zebrafish FGF19-2002Z Recombinant Zebrafish FGF19 Mammalian Cell His
    • Involved Pathway
    • Protein Function
    • Interacting Protein
    • FGF19 Related Articles
    • FGF19 Related Research Area
    • FGF19 Related Signal Pathway

    FGF19 involved in several pathways and played different roles in them. We selected most pathways FGF19 participated on our site, such as MAPK signaling pathway, Ras signaling pathway, Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with FGF19 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Ras signaling pathwayGNGT2;PLA2G2D;PLA2G2F;TEK;CALM3;PLA2G3;PAK3;Pdgfa&Pdgfb;GRIN1
    Rap signaling pathwayFGF12;BRAF;FGF3;LPAR4;KITLG;PARD6B;LPAR3;RALGDS;KLK1B4
    Regulation of actin cytoskeletonINS1;ROCK2A;PIP5K1BB;CHRM5B;MAP2K1;ABI2B;ROCK2B;FGF19;MAP2K2A

    FGF19 has several biochemical functions, for example, protein binding, protein kinase binding, protein phosphatase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FGF19 itself. We selected most functions FGF19 had, and list some proteins which have the same functions with FGF19. You can find most of the proteins on our site.

    Function Related Protein
    protein bindingFBXW11;CCDC137;CSRP2BP;F2R;VHL;CSNK1D;ZBTB24;NUDCD3;KIAA1958
    protein kinase bindingPXN;FBXO5;SNAP91;HCLS1;CDKN2A;DAXX;PPP1CB;DNAJC3;ACTA2
    protein phosphatase bindingCDC27;TRAF2;SHOC2;CTNNB1;LCK;KAT2A;JUPA;ITPR1;PPP1R3C

    FGF19 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FGF19 here. Most of them are supplied by our site. Hope this information will be useful for your research of FGF19.

    Walters, JRF; et al. Bile acid diarrhoea and FGF19: new views on diagnosis, pathogenesis and therapy. NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY 11:426-434(2014).
    Kong, B; Guo, GL; et al. Soluble Expression of Disulfide Bond Containing Proteins FGF15 and FGF19 in the Cytoplasm of Escherichia coli. PLOS ONE 9:-(2014).
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