FGF19-48H
Optional Service: Optional requirements on this protein
Product Overview :
Recombinant Human FGF19 Protein (aa 25-216) is produced by HEK 293 cells expression system. This protein is fused with a His tag at the C-terminus.
Description :
FGF-19 (Fibroblast growth factor 19) is involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. FGF-19 plays an important role in brain development during embryogenesis. FGF-19 binds only to FGF receptor 4 (FGFR4). Activity requires the presence of KLB.
Source :
HEK293
Species :
Human
Tag :
His
Form :
Lyophilized from 0.2μm-filtered solution in 1x PBS.
Molecular Mass :
22kDa (SDS-PAGE)
Protein length :
aa 25-216
Endotoxin :
<0.06EU/μg purified protein (LAL test; Lonza).
Purity :
≥90% (SDS-PAGE)
Notes :
Avoid freeze/thaw cycles.
Stability :
Stable for at least 1 year after receipt when stored at -20 centigrade. Working aliquots are stable for up to 3 months when stored at -20 centigrade.
Storage :
Short Term Storage at +4 centigrade. Long Term Storage at -20 centigrade.
Reconstitution :
10µg vial: Reconstitute with 100 µl sterile water to a concentration of 0.1mg/ml. 50µg vial: Reconstitute with 50 µl sterile water to a concentration of 1mg/ml. Add 1X PBS to the desired protein concentration.
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.