Recombinant Human FGF19
Cat.No. : | FGF19-27597TH |
Product Overview : | Recombinant FGF19 fragment (Human) containing 195 amino acid residues. |
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- Specification
- Gene Information
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Description : | The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumor growth and invasion. This growth factor is a high affinity, heparin dependent ligand for FGFR4. Expression of this gene was detected only in fetal but not adult brain tissue. Synergistic interaction of the chick homolog and Wnt-8c has been shown to be required for initiation of inner ear development. |
Source : | E. coli |
Tissue specificity : | Expressed in fetal brain, cartilage, retina, and adult gall bladder. |
Form : | Lyophilised:Centrifuge the vial prior to opening.Reconstitute in water to a concentration of 0.1-1.0 mg/ml.This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or -20°C for future use.Repeated freeze thaw cycles will r |
Purity : | >95% by SDS-PAGE |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
Sequences of amino acids : | MRPLAFSDAG PHVHYGWGDP IRLRHLYTSG PHGLSSCFLR IRADGVVDCA RGQSAHSLLE IKAVALRTVA IKGVHSVRYL CMGADGKMQG LLQYSEEDCA FEEEIRPDGY NVYRSEKHRL PVSLSSAKQR QLYKNRGFLP LSHFLPMLPM VPEEPEDLRG HLESDMFSSP LETDSMDPFG LVTGLEAVRS PSFEK |
Sequence Similarities : | Belongs to the heparin-binding growth factors family. |
Publication : |
The Cancer-Associated< i> FGFR4-G388R Polymorphism Enhances Pancreatic Insulin Secretion and Modifies the Risk of Diabetes. (2013)
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Gene Name : | FGF19 fibroblast growth factor 19 [ Homo sapiens ] |
Official Symbol : | FGF19 |
Synonyms : | FGF19; fibroblast growth factor 19; |
Gene ID : | 9965 |
mRNA Refseq : | NM_005117 |
Protein Refseq : | NP_005108 |
MIM : | 603891 |
Uniprot ID : | O95750 |
Chromosome Location : | 11q13.1 |
Pathway : | Downstream signaling of activated FGFR, organism-specific biosystem; FGF signaling pathway, organism-specific biosystem; FGFR ligand binding and activation, organism-specific biosystem; FGFR4 ligand binding and activation, organism-specific biosystem; FRS2-mediated cascade, organism-specific biosystem; |
Function : | fibroblast growth factor receptor binding; growth factor activity; protein binding; protein tyrosine kinase activity; |
Products Types
◆ Recombinant Protein | ||
FGF19-7336H | Recombinant Human FGF19 protein(Phe27-Lys216) | +Inquiry |
FGF19-032H | Recombinant Human FGF19 Protein | +Inquiry |
FGF19-48H | Recombinant Human FGF19 Protein, His-tagged | +Inquiry |
FGF19-4109H | Recombinant Human FGF19 Protein, GST-tagged | +Inquiry |
FGF19-1485H | Recombinant Human FGF19 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
FGF19-6244HCL | Recombinant Human FGF19 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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