Recombinant Human FGF19 protein, His-tagged
Cat.No. : | FGF19-3970H |
Product Overview : | Recombinant Human FGF19 protein(30-216 aa), fused to His tag, was expressed in E. coli. |
Availability | July 26, 2024 |
Unit | |
Price | |
Qty |
- Specification
- Gene Information
- Related Products
- Download
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | The purified protein was Lyophilized from sterile PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH7.4). 5 % trehalose and 5 % mannitol are added as protectant before lyophilization. The elution buffer contain 300mM imidazole. |
Protein Length : | 30-216 aa |
AA Sequence : | AGPHVHYGWGDPIRLRHLYTSGPHG LSSCFLRIRADGVVDCARGQSAHSL LEIKAVALRTVAIKGVHSVRYLCMG ADGKMQGLLQYSEEDCAFEEEIRPD GYNVYRSEKHRLPVSLSSAKQRQLY KNRGFLPLSHFLPMLPMVPEEPEDL RGHLESDMFSSPLETDSMDPFGLVT GLEAVRSPSFEK |
Purity : | 90%, by SDS-PAGE with Coomassie Brilliant Blue staining. |
Storage : | Short-term storage: Store at 2-8°C for (1-2 weeks). Long-term storage: Aliquot and store at -20°C to -80°C for up to 3 months, buffer containing 50% glycerol is recommended for reconstitution. Avoid repeat freeze-thaw cycles. |
Reconstitution : | Reconstitute at 0.25 µg/μl in 200 μl sterile water for short-term storage. Reconstitution with 200 μl 50% glycerol solution is recommended for longer term storage. |
Gene Name : | FGF19 fibroblast growth factor 19 [ Homo sapiens ] |
Official Symbol : | FGF19 |
Synonyms : | FGF19; fibroblast growth factor 19; FGF-19; |
Gene ID : | 9965 |
mRNA Refseq : | NM_005117 |
Protein Refseq : | NP_005108 |
MIM : | 603891 |
UniProt ID : | O95750 |
Products Types
◆ Recombinant Protein | ||
FGF19-032H | Recombinant Human FGF19 Protein | +Inquiry |
FGF19-1484H | Recombinant Human FGF19 Protein, His-tagged | +Inquiry |
FGF19-1485H | Recombinant Human FGF19 Protein, His-tagged | +Inquiry |
FGF19-4109H | Recombinant Human FGF19 Protein, GST-tagged | +Inquiry |
FGF19-7336H | Recombinant Human FGF19 protein(Phe27-Lys216) | +Inquiry |
◆ Lysates | ||
FGF19-6244HCL | Recombinant Human FGF19 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Reviews
- Q&As
Customer Reviews (3)
Write a reviewTop-notch protein quality! It's our go-to for reliable and reproducible results.
This product simplifies our research. It's a reliable tool that we can count on.
If you're in the lab, you need this product. It streamlines processes and is a lab necessity.
Q&As (5)
Ask a questionFGF19 expression is regulated by bile acids and other factors. Its secretion and activity are influenced by nutrient availability, signaling pathways, and interactions with bile acid receptors.
Targeting FGF19 holds therapeutic potential for metabolic disorders. Challenges include achieving tissue-specific effects and understanding the long-term consequences of manipulating FGF19 signaling.
FGF19 regulates bile acid synthesis in the liver and influences the enterohepatic circulation, impacting metabolic health by modulating lipid and glucose metabolism.
FGF19 influences gut hormone secretion, including the release of glucagon-like peptide-1 (GLP-1). This regulation contributes to its metabolic effects, such as enhanced insulin sensitivity and reduced food intake.
Dysregulation of FGF19 is implicated in metabolic diseases, including obesity and NAFLD. Altered FGF19 signaling may contribute to aberrant bile acid and lipid metabolism in these conditions.
Ask a Question for All FGF19 Products
Required fields are marked with *
My Review for All FGF19 Products
Required fields are marked with *
Inquiry Basket