Recombinant Rat Fgf19 protein, His-tagged
Cat.No. : | Fgf19-1815R |
Product Overview : | Recombinant Rat Fgf19 aa. (Gly25~Lys218) fused with N-terminal His tag was produced in E. coli cells. |
- Specification
- Gene Information
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Description : | Member of the fibroblast growth factor (FGF) family; implicated in activities including embryonic development, cell growth, morphogenesis, tissue growth, and tumor growth and invasion. |
Source : | E. coli |
Species : | Rat |
Tag : | His |
Form : | Freeze-dried powder |
Molecular Mass : | 24kDa as determined by SDS-PAGE reducing conditions. |
Protein length : | Gly25~Lys218 |
Endotoxin : | <1.0EU per 1ug (determined by the LAL method) |
Purity : | >95% |
Applications : | SDS-PAGE; WB; ELISA; IP; CoIP; Reporter Assays; Purification; Amine Reactive Labeling. |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Concentration : | 200μg/mL |
Storage buffer : | PBS, pH7.4, containing 1mM DTT, 5% trehalose, 0.01% sarcosyl and Proclin300. |
Reconstitution : | Reconstitute in PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex. |
Isoelectric Point : | 6.6 |
Gene Name : | Fgf19 fibroblast growth factor 19 [ Rattus norvegicus (Norway rat) ] |
Official Symbol : | Fgf19 |
Synonyms : | Fgf19; fibroblast growth factor 19; Fgf15; fibroblast growth factor 19; fibroblast growth factor 15 |
Gene ID : | 170582 |
mRNA Refseq : | NM_130753.1 |
Protein Refseq : | NP_570109.1 |
UniProt ID : | Q8VI81 |
Products Types
◆ Recombinant Protein | ||
FGF19-4109H | Recombinant Human FGF19 Protein, GST-tagged | +Inquiry |
FGF19-032H | Recombinant Human FGF19 Protein | +Inquiry |
FGF19-1485H | Recombinant Human FGF19 Protein, His-tagged | +Inquiry |
FGF19-1484H | Recombinant Human FGF19 Protein, His-tagged | +Inquiry |
FGF19-7336H | Recombinant Human FGF19 protein(Phe27-Lys216) | +Inquiry |
◆ Lysates | ||
FGF19-6244HCL | Recombinant Human FGF19 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionFGF19 expression is regulated by bile acids and other factors. Its secretion and activity are influenced by nutrient availability, signaling pathways, and interactions with bile acid receptors.
Targeting FGF19 holds therapeutic potential for metabolic disorders. Challenges include achieving tissue-specific effects and understanding the long-term consequences of manipulating FGF19 signaling.
FGF19 regulates bile acid synthesis in the liver and influences the enterohepatic circulation, impacting metabolic health by modulating lipid and glucose metabolism.
FGF19 influences gut hormone secretion, including the release of glucagon-like peptide-1 (GLP-1). This regulation contributes to its metabolic effects, such as enhanced insulin sensitivity and reduced food intake.
Dysregulation of FGF19 is implicated in metabolic diseases, including obesity and NAFLD. Altered FGF19 signaling may contribute to aberrant bile acid and lipid metabolism in these conditions.
Customer Reviews (3)
Write a reviewTop-notch protein quality! It's our go-to for reliable and reproducible results.
This product simplifies our research. It's a reliable tool that we can count on.
If you're in the lab, you need this product. It streamlines processes and is a lab necessity.
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