Active Recombinant Human FGF19 Protein (Arg23-Lys216), C-His tagged, Animal-free, Carrier-free

• Cat.No.: FGF19-325H
• Product Overview: Recombinant Human FGF19 Protein (Arg23-Lys216) with C-His tag was expressed in E. coli and Animal-free as well as Carrier-free.

Specification

• Description: Fibroblast Growth Factors-19 (FGF-19) is a 24 kDa member of the fibroblast Growth Factors with 216 amino acid residues. FGF-19 is mainly secreted from cholangiocytes, ductal cells. FGF-19 involved cell proliferation, glucose and bile acid metabolism via FGFR4 pathway.
• Source: E. coli
• Species: Human
• Tag: C-His
• Form: Lyophilized
• Bio-activity: Measure by its ability to induce 3T3 cells proliferation. The ED50 for this effect is < 51 ng/mL.
• Molecular Mass: The protein has a calculated MW of 22.62 kDa.
  The protein migrates as 24 kDa under reducing condition (SDS-PAGE analysis).
• Protein Length: Arg23-Lys216
• Endotoxin: < 0.1 EU/μg of the protein by the LAL method.
• Purity: >95% as determined by SDS-PAGE analysis.
• Storage: This product is stable after storage at:
  -20 centigrade for 12 months in lyophilized state from date of receipt.
  -20 or -80 centigrade for 1 month under sterile conditions after reconstitution.
  Avoid repeated freeze/thaw cycles.
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 8.0.
• Reconstitution: It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.
• Shipping: The product is shipped with polar packs. Upon receipt, store it immediately at -20 centigrade or lower for long term storage.

Gene Information

• Gene Name: FGF19 fibroblast growth factor 19 [ Homo sapiens (human) ]
• Official Symbol: FGF19
• Synonyms: FGF19; fibroblast growth factor 19; FGF-19
• Gene ID: 9965
• mRNA Refseq: NM_005117
• Protein Refseq: NP_005108
• MIM: 603891
• UniProt ID: O95750