Recombinant Human FGF19 protein(Phe27-Lys216)
Cat.No. : | FGF19-7336H |
Product Overview : | Recombinant Human FGF19 protein(O95750-1)(Phe27-Lys216) was expressed in E. coli. |
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similar : | FGF19 |
Alias : | FGF19; fibroblast growth factor 19; FGF-19; |
Source : | E. coli |
Species : | Human |
Conjugate : | N/A |
Tag : | Non |
Protein length : | Phe27-Lys216 |
Form : | Lyophilized from sterile 50mM Tris, 300mM NaCl, pH 8.5. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
MolecularMass : | The recombinant human FGF19 consists of 191 amino acids and predicts a molecular mass of 21.4 KDa. It migrates as an approximately 23 KDa band in SDS-PAGE under reducing conditions. |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method |
Purity : | > 90 % as determined by SDS-PAGE |
Storage : | Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
GeneName : | FGF19 fibroblast growth factor 19 [ Homo sapiens ] |
GeneNameWeblink : | 9965 |
OfficialSymbol : | FGF19 |
OfficialSymbolWeblink : | 9965 |
GeneIDWeblink : | 9965 |
mRNARefseq : | NM_005117 |
mRNARefseqWeblink : | NM_005117.2 |
ProteinRefseqWeblink : | NP_005108.1 |
MIMWeblink : | 603891 |
UniProtID : | O95750 |
UniProtIDWeblink : | O95750 |
Synonyms : | FGF19; fibroblast growth factor 19; FGF-19; |
Gene ID : | 9965 |
MIM : | 603891 |
Synonyms : | FGF19; fibroblast growth factor 19; FGF-19; |
Gene ID : | 9965 |
MIM : | 603891 |
Products Types
◆ Recombinant Protein | ||
FGF19-48H | Recombinant Human FGF19 Protein, His-tagged | +Inquiry |
FGF19-121F | Active Recombinant Human FGF19 Protein (195 aa) | +Inquiry |
FGF19-75H | Recombinant Active Human FGF19 Protein, His-tagged(C-ter) | +Inquiry |
FGF19-325H | Active Recombinant Human FGF19 Protein (Arg23-Lys216), C-His tagged, Animal-free, Carrier-free | +Inquiry |
FGF19-032H | Recombinant Human FGF19 Protein | +Inquiry |
◆ Lysates | ||
FGF19-6244HCL | Recombinant Human FGF19 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewTop-notch protein quality! It's our go-to for reliable and reproducible results.
This product simplifies our research. It's a reliable tool that we can count on.
If you're in the lab, you need this product. It streamlines processes and is a lab necessity.
Q&As (5)
Ask a questionFGF19 expression is regulated by bile acids and other factors. Its secretion and activity are influenced by nutrient availability, signaling pathways, and interactions with bile acid receptors.
Targeting FGF19 holds therapeutic potential for metabolic disorders. Challenges include achieving tissue-specific effects and understanding the long-term consequences of manipulating FGF19 signaling.
FGF19 regulates bile acid synthesis in the liver and influences the enterohepatic circulation, impacting metabolic health by modulating lipid and glucose metabolism.
FGF19 influences gut hormone secretion, including the release of glucagon-like peptide-1 (GLP-1). This regulation contributes to its metabolic effects, such as enhanced insulin sensitivity and reduced food intake.
Dysregulation of FGF19 is implicated in metabolic diseases, including obesity and NAFLD. Altered FGF19 signaling may contribute to aberrant bile acid and lipid metabolism in these conditions.
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