FGF20 Protein


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Official Full Name Fgf20 fibroblast growth factor 20
Background Fibroblast growth factor 21(FGF-21) is a novel protein that has been implicated in the regulation of lipid and glucose metabolism under fasting and ketotic conditions. In murine models, FGF-21 is predominantly expressed in liver, but it also expressed in adipose tissue and pancreatic -cells. FGF-21 stimulates glucose uptake in adipocytes. It also protects animals from diet-induced obesity when overexpressed in transgenic mice and lowers blood glucose and triglyceride levels when administered to diabetic rodents. When administered daily for 6 weeks to diabetic rhesus monkeys, FGF-21 caused a dramatic decline in fasting plasma glucose, fructosamine, triglycerides, insulin, and glucagon. Furthermore, elevated plasma FGF-21 concentrations in humans appear to be related to the presence of hepatic and peripheral insulin resistance.
Synonyms FGF20; fibroblast growth factor 20; FGF-20;
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • E. coli
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • His(C-ter)
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human FGF20-15H Active Recombinant Human FGF20 protein, His-tagged E.coli His Inquiry
    Human FGF20-331H Active Recombinant Human FGF20 Protein E.coli N/A Inquiry
    Human FGF20-12869H Recombinant Human FGF20, GST-tagged E.coli GST Inquiry
    Human FGF20-178H Recombinant Human Fibroblast Growth Factor 20 E.coli N/A Inquiry
    Human FGF20-19H Recombinant Human FGF20 protein, His-tagged E.coli His Inquiry
    Mouse FGF20-5848M Recombinant Mouse FGF20 Protein Mammalian Cell His Inquiry
    Rat FGF20-2332R Recombinant Rat FGF20 Protein Mammalian Cell His Inquiry
    Human FGF20-6243HCL Recombinant Human FGF20 293 Cell Lysate HEK293 N/A Inquiry
    Human FGF20-033H Recombinant Human FGF20 Protein E. coli Inquiry
    Mouse Fgf20-2911M Recombinant Mouse Fgf20 protein E.coli N/A Inquiry
    Mouse Fgf20-2912M Recombinant Mouse Fgf20 protein, His-tagged E.coli His Inquiry
    Human FGF20-80H Recombinant Active Human FGF20 Protein, His-tagged(C-ter) E.coli His(C-ter) Inquiry

    FGF20 involved in several pathways and played different roles in them. We selected most pathways FGF20 participated on our site, such as MAPK signaling pathway, Ras signaling pathway, Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with FGF20 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    MAPK signaling pathway FGF3; MAP2K2B; PRKACA; FGF14; NTRK1; MRAS; ECSIT; JUND; CD14; MAP3K2
    Ras signaling pathway FIGF; Fgf15; PDGFRB; CALML5; VEGFA; FGFR4; PTPN11; PLA2G4D; PLA2G4F; RASSF1
    Rap signaling pathway PFN1; RAC2; SRC; PIK3R3; ITGB1; FGF7; Kitl; ARAP3; RAPGEF5; SKAP1
    PIK-Akt signaling pathway IFNA6; ITGA3; RXRA; IFNA21; YWHAH; TLR4; AKT2; GYS2; FGFR4; PRLR
    Regulation of actin cytoskeleton PTK2AB; BRAF; CHRM5B; RAC3B; ITGA1; RAC1B; ACTN1; GSNA; ARHGEF6; GSN
    Pathways in cancer CDC42; FASLG; CCNA1; GNG8; IL6; MITF; IGF1R; RALGDS; IL-8; PIK3CD
    Melanoma RB1; PIK3R3; FGF14; MITF; FGF6; PIK3R2; PDGFA; FGF10; PIK3R5; FGF19

    FGF20 has several biochemical functions, for example, fibroblast growth factor receptor binding, growth factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FGF20 itself. We selected most functions FGF20 had, and list some proteins which have the same functions with FGF20. You can find most of the proteins on our site.

    Function Related Protein
    fibroblast growth factor receptor binding FGF8; FGF20B; FGF6A; FGF10B; FGF2; FGF8A; FGF5; FGF20; FGF21; FGF1
    growth factor activity GDF6; HBEGFB; MANF; CXCL1; RABEP1; TGFB1A; GH1; TYMP; FIGF; Fgf15

    FGF20 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FGF20 here. Most of them are supplied by our site. Hope this information will be useful for your research of FGF20.

    Munnamalai, V; Hayashi, T; et al. Notch Prosensory Effects in the Mammalian Cochlea Are Partially Mediated by Fgf20. JOURNAL OF NEUROSCIENCE 32:12876-12884(2012).
    Hayashi, T; Ray, CA; et al. Fgf20 is required for sensory epithelial specification in the developing cochlea. JOURNAL OF NEUROSCIENCE 28:5991-5999(2008).

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