FGF20 involved in several pathways and played different roles in them. We selected most pathways FGF20 participated on our site, such as MAPK signaling pathway, Ras signaling pathway, Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with FGF20 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name |
Pathway Related Protein |
| MAPK signaling pathway |
FGF3; MAP2K2B; PRKACA; FGF14; NTRK1; MRAS; ECSIT; JUND; CD14; MAP3K2 |
| Ras signaling pathway |
FIGF; Fgf15; PDGFRB; CALML5; VEGFA; FGFR4; PTPN11; PLA2G4D; PLA2G4F; RASSF1 |
| Rap signaling pathway |
PFN1; RAC2; SRC; PIK3R3; ITGB1; FGF7; Kitl; ARAP3; RAPGEF5; SKAP1 |
| PIK-Akt signaling pathway |
IFNA6; ITGA3; RXRA; IFNA21; YWHAH; TLR4; AKT2; GYS2; FGFR4; PRLR |
| Regulation of actin cytoskeleton |
PTK2AB; BRAF; CHRM5B; RAC3B; ITGA1; RAC1B; ACTN1; GSNA; ARHGEF6; GSN |
| Pathways in cancer |
CDC42; FASLG; CCNA1; GNG8; IL6; MITF; IGF1R; RALGDS; IL-8; PIK3CD |
| Melanoma |
RB1; PIK3R3; FGF14; MITF; FGF6; PIK3R2; PDGFA; FGF10; PIK3R5; FGF19 |
FGF20 has several biochemical functions, for example, fibroblast growth factor receptor binding, growth factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FGF20 itself. We selected most functions FGF20 had, and list some proteins which have the same functions with FGF20. You can find most of the proteins on our site.
| Function |
Related Protein |
| fibroblast growth factor receptor binding |
FGF8; FGF20B; FGF6A; FGF10B; FGF2; FGF8A; FGF5; FGF20; FGF21; FGF1 |
| growth factor activity |
GDF6; HBEGFB; MANF; CXCL1; RABEP1; TGFB1A; GH1; TYMP; FIGF; Fgf15 |
FGF20 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FGF20 here. Most of them are supplied by our site. Hope this information will be useful for your research of FGF20.
Munnamalai, V; Hayashi, T; et al. Notch Prosensory Effects in the Mammalian Cochlea Are Partially Mediated by Fgf20. JOURNAL OF NEUROSCIENCE 32:12876-12884(2012).
Hayashi, T; Ray, CA; et al. Fgf20 is required for sensory epithelial specification in the developing cochlea. JOURNAL OF NEUROSCIENCE 28:5991-5999(2008).
