FGF5

  • Official Full Name

    fibroblast growth factor 5

  • Overview

    The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified as an oncogene, which confers transforming potential when transfected into mammalian cells. Targeted disruption of the homolog of this gene in mouse resulted in the phenotype of abnormally long hair, which suggested a function as an inhibitor of hair elongation. Alternatively spliced transcript variants encoding different isoforms have been identified.
  • Synonyms

    FGF5; fibroblast growth factor 5; heparin-binding growth factor 5; HBGF-5; Smag-82;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E. coli
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • C
  • His
  • GST
  • His (Fc)
  • Avi
  • His(C
  • ter)
  • His|GST
  • N/A
  • N
  • Myc
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human FGF5-172H Recombinant Human Fibroblast Growth Factor 5 E.coli N/A
Human FGF5-28880TH Recombinant Human FGF5 E.coli N/A
Human FGF5-501H Recombinant Human FGF5 Protein, His/GST-tagged E.coli His/GST Glu23~Gly268
Human FGF5-6239HCL Recombinant Human FGF5 293 Cell Lysate HEK293 N/A
Human FGF5-6238HCL Recombinant Human FGF5 293 Cell Lysate HEK293 N/A
Human FGF5-039H Active Recombinant Human FGF5 Protein E.coli
Human FGF5-4835HF Recombinant Full Length Human FGF5 Protein, GST-tagged In Vitro Cell Free System GST 123 amino acids
Human FGF5-4114H Recombinant Human FGF5 Protein, GST-tagged Wheat Germ GST
Human FGF5-88H Recombinant Active Human FGF5 Protein, His-tagged(C-ter) E.coli His(C-ter)
Human FGF5-1497H Recombinant Human FGF5 Protein, His-tagged E.coli N-His Glu23-Gly268
Human FGF5-97H Active Recombinant Human FGF5 Protein (Ala18-Gly268), C-His tagged, Animal-free, Carrier-free E.coli C-His Ala18-Gly268
Human FGF5-89H Active Recombinant Human FGF5 Protein E.coli
Human FGF5-7539H Recombinant Human FGF5 protein(21-268aa), His-GST&Myc-tagged E. coli N-His-GST&C-Myc 21-268aa
Mouse FGF5-5854M Recombinant Mouse FGF5 Protein Mammalian Cell His
Mouse Fgf5-876M Recombinant Mouse Fgf5 protein, His-tagged E.coli N-His 21-264aa
Mouse FGF5-3236M-B Recombinant Mouse FGF5 Protein Pre-coupled Magnetic Beads HEK293
Mouse FGF5-3236M Recombinant Mouse FGF5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Fgf5-8964M Recombinant Mouse Fgf5 protein, His&Myc-tagged E.coli N-His&C-Myc 21-264aa
Rat FGF5-2334R Recombinant Rat FGF5 Protein Mammalian Cell His
Rat FGF5-1991R-B Recombinant Rat FGF5 Protein Pre-coupled Magnetic Beads HEK293
Rat FGF5-1991R Recombinant Rat FGF5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish FGF5-1951Z Recombinant Zebrafish FGF5 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource
  • FGF5 Related Signal Pathway

FGF5 involved in several pathways and played different roles in them. We selected most pathways FGF5 participated on our site, such as MAPK signaling pathway, Ras signaling pathway, Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with FGF5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
MAPK signaling pathwayECSIT;RPS6KA5;MAP3K11;GNG12A;RAP1AB;RPS6KA2;PPM1B;CACNA1G;MAP3K14
Ras signaling pathwayFGFR1;FGF21;FGFR3;PAK2;MAPK3;RASA1;FGF1;INS2;NGF
Rap signaling pathwayMET;ITGAL;FGF11;ARAP3;FGF12;CALML3;ID1;SIPA1L1;RAP1GAP
PIK-Akt signaling pathwayIFNA1;PDGFA;COL6A6;INS2;GNG4;TLR2;PCK1;PPP2R5E;PIK3CD
Regulation of actin cytoskeletonVCL;F2;FGF5;WASLB;RAC1A;DIAP3;PIK3R1;PAK7;PPP1CAB
Pathways in cancerFZD2;SMAD4;WNT8A;FZD5;GNAI2;FZD3;WNT3;TGFA;MAPK10
MelanomaPDGFB;FGF5;AKT1;MAP2K2;MITF;BRAF;CCND1;FGF2;BAD

FGF5 has several biochemical functions, for example, fibroblast growth factor receptor binding, growth factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FGF5 itself. We selected most functions FGF5 had, and list some proteins which have the same functions with FGF5. You can find most of the proteins on our site.

Function Related Protein
fibroblast growth factor receptor bindingFGF18A;FGF20B;FGF22;FGF1A;FGF10A;FGF4;FGF9;FGF6B;KLB
growth factor activityIGF3;OSGIN1;FGF6A;BMP7B;GDF9;NENF;GDF6;FGF14;PROK1

FGF5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FGF5 here. Most of them are supplied by our site. Hope this information will be useful for your research of FGF5.

EGF; FGFR2; FGFR4; MAPK1

Research Area

Related articles

Jeon, JH; Suh, HN; et al. Glucosamine-Induced OGT Activation Mediates Glucose Production Through Cleaved Notch1 and FoxO1, Which Coordinately Contributed to the Regulation of Maintenance of Self-Renewal in Mouse Embryonic Stem Cells. STEM CELLS AND DEVELOPMENT 23:2067-2079(2014).
Hirano, K; Van Kuppevelt, TH; et al. The transition of mouse pluripotent stem cells from the naive to the primed state requires Fas signaling through 3-O sulfated heparan sulfate structures recognized by the HS4C3 antibody. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 430:1175-1181(2013).
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