Active Recombinant Human FGF5 Protein

Cat.No. : FGF5-039H
Product Overview : The mature recombinant human FGF-5 protein consists of 243 amino acids (26-268) without tag was expressed in E. coli.
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Description : The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified as an oncogene, which confers transforming potential when transfected into mammalian cells. Targeted disruption of the homolog of this gene in mouse resulted in the phenotype of abnormally long hair, which suggested a function as an inhibitor of hair elongation. Alternatively spliced transcript variants encoding different isoforms have been identified.
Source : E. coli
Species : Human
Bio-activity : Measured in a cell proliferation assay using NR6R­3T3 mouse fibroblast cells. The ED50 for this effect is 2-10 ng/mL in the presence of 1 μg/mL of heparin.
Molecular Mass : 27 kDa
Product-Related Proteins : 26-268
Endotoxin : < 0.1 EU/μg of the protein as determined by the LAL method
Purity : > 95 % as determined by SDS-PAGE
Storage : At -80 centigrade. Avoid repeated freeze-thaw cycles.
Storage Buffer : PBS
Gene Name : FGF5 fibroblast growth factor 5 [ Homo sapiens (human) ]
Official Symbol : FGF5
Synonyms : FGF5; fibroblast growth factor 5; HBGF-5; TCMGLY; Smag-82; fibroblast growth factor 5; heparin-binding growth factor 5
Gene ID : 2250
mRNA Refseq : NM_004464
Protein Refseq : NP_004455
MIM : 165190
UniProt ID : P12034

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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