FGL2
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Official Full Name
fibrinogen-like 2
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Overview
The protein encoded by this gene is a secreted protein that is similar to the beta- and gamma-chains of fibrinogen. The carboxyl-terminus of the encoded protein consists of the fibrinogen-related domains (FRED). The encoded protein forms a tetrameric complex which is stabilized by interchain disulfide bonds. This protein may play a role in physiologic functions at mucosal sites. -
Synonyms
FGL2; fibrinogen-like 2; fibroleukin; pT49; T49; fibrinogen-like protein 2;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rat
- Rhesus Macaque
- Zebrafish
- CHO
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- Yeast
- Flag
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- Myc|DDK
- N/A
- N
- FGL2 Related Articles
- FGL2 Related Research Area
FGL2 involved in several pathways and played different roles in them. We selected most pathways FGL2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FGL2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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FGL2 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by FGL2 itself. We selected most functions FGL2 had, and list some proteins which have the same functions with FGL2. You can find most of the proteins on our site.
Function | Related Protein |
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FGL2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FGL2 here. Most of them are supplied by our site. Hope this information will be useful for your research of FGL2.
- Q&As
- Reviews
Q&As (5)
Ask a questionYes, targeting FGL2 protein has shown promise in preclinical studies as a potential therapeutic strategy for autoimmune diseases.
FGL2 protein has been implicated in liver fibrosis, cirrhosis, and hepatocellular carcinoma by promoting inflammation, fibrogenesis, and immune dysregulation.
Potential side effects may include immunosuppression, increased risk of infections, and dysregulation of immune homeostasis.
Enzyme-linked immunosorbent assay (ELISA) and immunohistochemistry are commonly used methods for detecting FGL2 protein in clinical samples.
FGL2 protein has been shown to promote cancer cell growth, invasion, and metastasis by modulating immune responses and promoting angiogenesis.
Customer Reviews (3)
Write a reviewBy utilizing the FGL2 protein, I can approach my research with unwavering confidence in its quality, along with the unparalleled support provided by its manufacturer.
Their expertise and prompt responsiveness exemplify their dedication to providing customers with solutions and guidance.
The FGL2 protein offers exceptional quality that seamlessly aligns with my experimental requirements.
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