FPR1

  • Official Full Name

    formyl peptide receptor 1

  • Overview

    This gene encodes a G protein-coupled receptor of mammalian phagocytic cells that is a member of the G-protein coupled receptor 1 family. The protein mediates the response of phagocytic cells to invasion of the host by microorganisms and is important in host defense and inflammation.
  • Synonyms

    FPR1; formyl peptide receptor 1; fMet-Leu-Phe receptor; FMLP; FPR; fMet Leu Phe receptor; FMLP Receptor; FMLPR; FPR 1; FPR receptor; FPR1_HUMAN; N formyl peptide chemoattractant receptor; N formyl peptide receptor; N formylpeptide chemoattractant receptor; N-formyl peptide receptor; N-formylpeptide chemoattractant receptor;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Assay Kits
  • Gorilla gorilla gorilla (Western lowland gorilla)
  • Homo sapiens (Human)
  • Human
  • Macaca mulatta (Rhesus macaque)
  • Mouse
  • Mus musculus (Mouse)
  • Pan troglodytes (Chimpanzee)
  • Pongo pygmaeus (Bornean orangutan)
  • E.coli
  • E.coli expression system
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • Flag|His
  • GST
  • His
  • His (Fc)
  • Avi
  • His|GST|Myc
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human FPR1-274H Recombinant Human FPR1 protein, GST-tagged Wheat Germ GST
Human FPR1-26376TH Recombinant Human FPR1 Flag/His
Human FPR1-263H Recombinant Human FPR1 protein Wheat Germ N/A
Human FPR1-2994H Recombinant Human FPR1 protein, His-tagged E.coli His 140-203 aa
Human FPR1-2489H Recombinant Human FPR1 Protein (306-350 aa), His-GST-Myc-tagged E.coli His/GST/Myc 306-350 aa
Human FPR1-676HF Recombinant Full Length Human FPR1 Protein In Vitro Cell Free System 350 amino acids
Human FPR1-1524H Recombinant Human FPR1 Protein, His&GST-tagged E.coli N-His&GST Arg267-Lys350
Human FPR1-2882H Recombinant Human FPR1 Protein (Arg163-Val242), N-GST tagged E.coli N-GST Arg163-Val242
Human FPR1-682HF Recombinant Full Length Human FPR1 Protein, GST-tagged In Vitro Cell Free System GST 350 amino acids
Mouse FPR1-6022M Recombinant Mouse FPR1 Protein Mammalian Cell His
Mouse FPR1-2444M Recombinant Mouse FPR1 Protein (1-35 aa), His-GST-Myc-tagged E.coli His/GST/Myc 1-35 aa
Mouse FPR1-3346M Recombinant Mouse FPR1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse FPR1-3346M-B Recombinant Mouse FPR1 Protein Pre-coupled Magnetic Beads HEK293
Gorilla gorilla gorilla (Western lowland gorilla) RFL15648GF Recombinant Full Length Gorilla Gorilla Gorilla Fmet-Leu-Phe Receptor(Fpr1) Protein, His-Tagged E.coli expression system His Full Length (1-346)
Homo sapiens (Human) RFL32978HF Recombinant Full Length Human Fmet-Leu-Phe Receptor(Fpr1) Protein, His-Tagged E.coli expression system His Full Length (1-350)
Macaca mulatta (Rhesus macaque) RFL7630MF Recombinant Full Length Macaca Mulatta (Rhesus Macaque) Fmet-Leu-Phe Receptor(Fpr1) Protein, His-Tagged E.coli expression system His Full Length (1-346)
Mus musculus (Mouse) RFL2248MF Recombinant Full Length Mouse Fmet-Leu-Phe Receptor(Fpr1) Protein, His-Tagged E.coli expression system His Full Length (1-364)
Pan troglodytes (Chimpanzee) RFL29019PF Recombinant Full Length Pan Troglodytes Fmet-Leu-Phe Receptor(Fpr1) Protein, His-Tagged E.coli expression system His Full Length (1-346)
Pongo pygmaeus (Bornean orangutan) RFL17980PF Recombinant Full Length Pongo Pygmaeus Fmet-Leu-Phe Receptor(Fpr1) Protein, His-Tagged E.coli expression system His Full Length (1-346)
Kit-0946 Progesterone Receptor Competitor Assay Kit, Red N/A
Kit-1238 FPR1 CHO-K1 β-Arrestin GPCR Assay Kit N/A
Kit-1239 FPR1 Total GPCR Internalization Assay Kit N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

FPR1 involved in several pathways and played different roles in them. We selected most pathways FPR1 participated on our site, such as Rap signaling pathway, Neuroactive ligand-receptor interaction, Staphylococcus aureus infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with FPR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Rap signaling pathwayPLCB3;RAC3;ID1;MAPK13;SIPA1L2;RASGRP3;PARD6A;PARD3;ITGB3
Neuroactive ligand-receptor interactionGRIA1;S1PR5;GABRG1;P2RX8;CHRNA7;LHB;TAAR14F;GRIK5;C3AR1
Staphylococcus aureus infectionFCGR1A;C3AR1;HLA-DMB;FCGR1;HLA-DMA;CFH;FCGR4;PLG;FPR3

FPR1 has several biochemical functions, for example, N-formyl peptide receptor activity, RAGE receptor binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FPR1 itself. We selected most functions FPR1 had, and list some proteins which have the same functions with FPR1. You can find most of the proteins on our site.

Function Related Protein
N-formyl peptide receptor activityFPR-RS6;FPR2;FPR-RS3;FPR-RS4;FPR1
RAGE receptor bindingS100A8;S100B;S100A9;S100A7;S100A13;S100A12;HMGB1;HMGB2;S100P
protein bindingPPCDC;ERLEC1;SPCS1;GGA2;TBX6;TLR4;ISG20L2;PPP2R3C;FSTL1
receptor activityRRBP1B;UNC13B;KLRK1;CD1D;GFRA1A;CD4;RTN4RL1;ANPEP;CLEC4E

FPR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FPR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of FPR1.

MAPK13; ADRBK1; MAPK3; lcrD

Gene Family

GPCRs

Research Area

Related articles

Charest-Morin, X; Roy, C; et al. Pharmacological profile of a bifunctional ligand of the formyl peptide receptor(1) fused to the myc epitope. INTERNATIONAL IMMUNOPHARMACOLOGY 25:229-234(2015).
Balderud, LZ; Murray, D; et al. Using the BioAssay Ontology for Analyzing High-Throughput Screening Data. JOURNAL OF BIOMOLECULAR SCREENING 20:402-415(2015).
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