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  • Official Full Name

    G protein-coupled receptor kinase interacting ArfGAP 1

  • Overview

    ARF GTPase-activating protein GIT1 is an enzyme that in humans is encoded by the GIT1 gene.
  • Synonyms

    GIT1; G protein-coupled receptor kinase interacting ArfGAP 1; G protein coupled receptor kinase interactor 1; ARF GTPase-activating protein GIT1; CAT1; CAT-1; ARF GAP GIT1; GRK-interacting protein 1; G protein-coupled receptor kinase interactor 1; G prote;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Mammalian cells
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GIT1-13268H Recombinant Human GIT1, His-tagged E.coli His C-term-325a.a.
Human GIT1-5926HCL Recombinant Human GIT1 293 Cell Lysate HEK293 N/A
Human GIT1-301196H Recombinant Human GIT1 protein, GST-tagged E.coli GST Leu470-Pro640
Human GIT1-982H-B Recombinant Human GIT1 Protein Pre-coupled Magnetic Beads HEK293
Human GIT1-3983H Recombinant Human GIT1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human GIT1-2814H Recombinant Human GIT1 protein, His-tagged E.coli His 471-640 aa
Human GIT1-982H Recombinant Human GIT1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human GIT1-1144HFL Recombinant Full Length Human GIT1 Protein, C-Flag-tagged Mammalian cells Flag
Mouse GIT1-6366M Recombinant Mouse GIT1 Protein Mammalian Cell His
Mouse GIT1-3568M-B Recombinant Mouse GIT1 Protein Pre-coupled Magnetic Beads HEK293
Mouse GIT1-3568M Recombinant Mouse GIT1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Git1-3215M Recombinant Mouse Git1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat GIT1-2544R Recombinant Rat GIT1 Protein Mammalian Cell His
Rat GIT1-2200R Recombinant Rat GIT1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat GIT1-2200R-B Recombinant Rat GIT1 Protein Pre-coupled Magnetic Beads HEK293
Chicken GIT1-5869C Recombinant Chicken GIT1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • GIT1 Related Articles
  • GIT1 Related Research Area

GIT1 involved in several pathways and played different roles in them. We selected most pathways GIT1 participated on our site, such as Endocytosis, Regulation of actin cytoskeleton, Epithelial cell signaling in Helicobacter pylori infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with GIT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Regulation of actin cytoskeletonFGF8;ITGB4;RHOAC;DIAP3;ACTG1;FGF8A;FGF22;FGF12;Fgf15
Epithelial cell signaling in Helicobacter pylori infectionATP6V0B;JAM3;MET;ATP6V0D1;MAPK13;CXCR2;ATP6V0D2;SRC;MAPK11

GIT1 has several biochemical functions, for example, GTPase activator activity, metal ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GIT1 itself. We selected most functions GIT1 had, and list some proteins which have the same functions with GIT1. You can find most of the proteins on our site.

Function Related Protein
metal ion bindingBMX;ASAP2;KLF17;NUFIP1;NMRK2;ZNF786;FTR50;KDM6A;CHN2
protein complex bindingTRAF2;ANKRD54;FADD;EPCAM;CFLAR;NFYB;BCAP31;ATF1;NOG

GIT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GIT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GIT1.


Fujikawa, A; Matsumoto, M; et al. Specific Dephosphorylation at Tyr-554 of Git1 by Ptprz Promotes Its Association with Paxillin and Hic-5. PLOS ONE 10:-(2015).
Hammer, A; Oladimeji, P; et al. Phosphorylation of tyrosine 285 of PAK1 facilitates beta PIX/GIT1 binding and adhesion turnover. FASEB JOURNAL 29:943-959(2015).
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