GLRX3

  • Official Full Name

    glutaredoxin 3

  • Overview

    This gene encodes a member of the glutaredoxin family. Glutaredoxins are oxidoreductase enzymes that reduce a variety of substrates using glutathione as a cofactor. The encoded protein binds to and modulates the function of protein kinase C theta. The encoded protein may also inhibit apoptosis and play a role in cellular growth, and the expression of this gene may be a marker for cancer. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 9. Alternatively spliced transcript variants have been observed for this gene.
  • Synonyms

    GLRX3; glutaredoxin 3; thioredoxin like 2 , TXNL2; glutaredoxin-3; bA500G10.4; GLRX4; glutaredoxin 4; GRX3; GRX4; PICOT; PKC interacting cousin of thioredoxin; PKC theta interacting protein; PKCq interacting protein; Thioredoxin like protein 2; OTTHUMP00000020746; OTTHUMP00000020747; OTTHUMP00000020748; PKCq-interacting protein; thioredoxin-like protein 2; PKC-theta-interacting protein; PKC-interacting cousin of thioredoxin; TXNL2; TXNL3;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
  • T7
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GLRX3-13313H Recombinant Human GLRX3, GST-tagged E.coli GST C-term-289a.a.
Human GLRX3-2405H Recombinant Human Glutaredoxin 3, His-tagged E.coli His
Human GLRX3-31637TH Recombinant Human GLRX3, His-tagged E.coli His
Human GLRX3-194H Recombinant Human GLRX3 protein, T7-tagged E.coli T7
Human GLRX3-5897HCL Recombinant Human GLRX3 293 Cell Lysate HEK293 N/A
Human GLRX3-5073H Recombinant Human GLRX3 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human GLRX3-4977H Recombinant Human GLRX3 Protein, GST-tagged Wheat Germ GST
Human GLRX3-989H Recombinant Human GLRX3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human GLRX3-627H Recombinant Human GLRX3 Protein, His-tagged E.coli His Val10~Ser117
Human GLRX3-2969H Recombinant Human GLRX3 protein, GST-tagged E.coli GST 1-335aa
Human GLRX3-5348HF Recombinant Full Length Human GLRX3 Protein, GST-tagged In Vitro Cell Free System GST 335 amino acids
Human GLRX3-1401HFL Recombinant Full Length Human GLRX3 Protein, C-Flag-tagged Mammalian cells Flag
Human GLRX3-989H-B Recombinant Human GLRX3 Protein Pre-coupled Magnetic Beads HEK293
Human GLRX3-2902H Recombinant Human GLRX3 Protein (Val10-Ser117), His tagged E.coli His Val10-Ser117
Mouse GLRX3-6424M Recombinant Mouse GLRX3 Protein Mammalian Cell His
Mouse GLRX3-3603M-B Recombinant Mouse GLRX3 Protein Pre-coupled Magnetic Beads HEK293
Mouse Glrx3-629M Recombinant Mouse Glrx3 Protein, His-tagged E.coli His Glu73~Val320
Mouse GLRX3-3603M Recombinant Mouse GLRX3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat GLRX3-2572R Recombinant Rat GLRX3 Protein Mammalian Cell His
Rat GLRX3-2227R Recombinant Rat GLRX3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat GLRX3-2227R-B Recombinant Rat GLRX3 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish GLRX3-1480Z Recombinant Zebrafish GLRX3 Mammalian Cell His
Chicken GLRX3-4797C Recombinant Chicken GLRX3 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • GLRX3 Related Research Area

GLRX3 involved in several pathways and played different roles in them. We selected most pathways GLRX3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with GLRX3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

GLRX3 has several biochemical functions, for example, electron carrier activity, iron-sulfur cluster binding, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GLRX3 itself. We selected most functions GLRX3 had, and list some proteins which have the same functions with GLRX3. You can find most of the proteins on our site.

Function Related Protein
electron carrier activityUQCR11;IDH3B;GRXCR1;HAAO;AIFM1;CYP1A2;DERL3;AOX4;COX7A2A
iron-sulfur cluster bindingAIFM4;REV3L;ISCUB;EXO5;DPYDB;FXN;PROZA;AOX3L1;RSAD1
metal ion bindingPLCH2;PPM1F;RASSF5;PPEF2;ZBED1;ZFP516;ZBTB7C;ZFP609;KLF2A
poly(A) RNA bindingMRPS31;FLYWCH2;GTL3;DNTTIP2;RALYL;C1orf131;PSPC1;MRPL9;MOV10
protein bindingTIA1;SF3A3;PTRH2;SEPT5;TOP1;KIFAP3;C21orf2;COMMD1;NUB1
protein disulfide oxidoreductase activityENOX2;GLRX2;GLRX3;TXN;GLRX5;DNAJC10;TXNRD3;ERO1L;GSTK1
protein kinase C bindingMARCKS;HINT1;HDAC7;CASQ2;PRKCSH;AKT1;AVPR1B;GNB2L1;DACT3

GLRX3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GLRX3 here. Most of them are supplied by our site. Hope this information will be useful for your research of GLRX3.

CIAPIN1; RGS20; PLSCR1; GRN

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