Recombinant Full Length Human GLRX3 Protein, C-Flag-tagged

• Cat.No.: GLRX3-1401HFL
• Product Overview: Recombinant Full Length Human GLRX3 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a member of the glutaredoxin family. Glutaredoxins are oxidoreductase enzymes that reduce a variety of substrates using glutathione as a cofactor. The encoded protein binds to and modulates the function of protein kinase C theta. The encoded protein may also inhibit apoptosis and play a role in cellular growth, and the expression of this gene may be a marker for cancer. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 9. Alternatively spliced transcript variants have been observed for this gene.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 37.3 kDa
• AA Sequence: MAAGAAEAAVAAVEEVGSAGQFEEL LRLKAKSLLVVHFWAPWAPQCAQMN EVMAELAKELPQVSFVKLEA EGVPEVSEKYEISSVPTFLFFKNSQ KIDRLDGAHAPELTKKVQRHASSGS FLPSANEHLKEDLNLRLKKL THAAPCMLFMKGTPQEPRCGFSKQM VEILHKHNIQFSSFDIFSDEEVRQG LKAYSSWPTYPQLYVSGELI GGLDIIKELEASEELDTICPKAPKL EERLKVLTNKASVMLFMKGNKQEAK CGFSKQILEILNSTGVEYET
  FDILEDEEVRQGLKAYSNWPTYPQL YVKGELVGGLDIVKELKENGELLPI LRGENTRTRPLEQKLISEEDLAAND ILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome

Gene Information

• Gene Name: GLRX3 glutaredoxin 3 [ Homo sapiens (human) ]
• Official Symbol: GLRX3
• Synonyms: GRX3; GRX4; GLRX4; PICOT; TXNL2; TXNL3
• Gene ID: 10539
• mRNA Refseq: NM_006541.5
• Protein Refseq: NP_006532.2
• MIM: 612754
• UniProt ID: O76003