Recombinant Human GLRX3 Protein, GST-tagged

• Cat.No.: GLRX3-4977H
• Product Overview: Human GLRX3 full-length ORF ( AAH05289, 1 a.a. - 335 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the glutaredoxin family. Glutaredoxins are oxidoreductase enzymes that reduce a variety of substrates using glutathione as a cofactor. The encoded protein binds to and modulates the function of protein kinase C theta. The encoded protein may also inhibit apoptosis and play a role in cellular growth, and the expression of this gene may be a marker for cancer. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 9. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 62.59 kDa
• AA Sequence: MAAGAAEAAVAAVEEVGSAGQFEEL LRLKAKSLLVVHFWAPWAPQCAQMN EVMAELAKELPQVSFVKLEAEGVPE VSEKYEISSVPTFLFFKNSQKIDRL DGAHAPELTKKVQRHASSGSFLPSA NEHLKEDLNLRLKKLTHAAPCMLFM KGTPQEPRCGFSKQMVEILHKHNIQ FSSFDIFSDEEVRQGLKAYSSWPTY PQLYVSGELIGGLDIIKELEASEEL DTICPKAPKLEERLKVLTNKASVML FMKGNKQEAKCGFSKQILEILNSTG VEYETFDILEDEEVRQGLKAYSNWP TYPQLYVKGELVGGLDIVKELKENG ELLPILRGEN
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: GLRX3 glutaredoxin 3 [ Homo sapiens ]
• Official Symbol: GLRX3
• Synonyms: GLRX3; glutaredoxin 3; thioredoxin like 2, TXNL2; glutaredoxin-3; bA500G10.4; GLRX4; glutaredoxin 4; GRX3; GRX4; PICOT; PKCq-interacting protein; thioredoxin-like protein 2; PKC-theta-interacting protein; PKC-interacting cousin of thioredoxin; TXNL2; TXNL3; FLJ11864
• Gene ID: 10539
• mRNA Refseq: NM_001199868
• Protein Refseq: NP_001186797
• MIM: 612754
• UniProt ID: O76003