- Involved Pathway
- Protein Function
- Interacting Protein
- GRB7 Related Articles
- GRB7 Related Gene Family
- GRB7 Related Signal Pathway
GRB7 involved in several pathways and played different roles in them. We selected most pathways GRB7 participated on our site, such as Angiopoietin receptor Tie2-mediated signaling, Cell surface interactions at the vascular wall, Downstream signal transduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with GRB7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
||Pathway Related Protein
|Angiopoietin receptor Tie2-mediated signaling||BMX;GRB14;GRB7;DOK2;ELF2;CRK;CDKN1A;ELF1;AGTR1|
|Cell surface interactions at the vascular wall||AMICA1;CEACAM1;FCER1GL;BSG;GRB7;CEACAM8;SLC16A8;ESAMA;SLC7A10|
|Downstream signal transduction||DUSP2;MOV10;WDR83;GRB7;LAMTOR2;FRS2A;FGF8B;SPRED2;IL17RD|
|EGFR1 Signaling Pathway||RALBA;ABI1B;RBB4L;CEBPA;DNM1;KLF11;PITPNA;KRT7;RALBB|
|EPHB forward signaling||EFNB3;ITSN1;EFNA5;EFNB2;EFNB1;GRB7|
|GRB7 events in ERBB2 signaling|
|Kit Receptor Signaling Pathway||SOCS4;DOK1B;SPRED2B;GRAPA;GRB10;DOK1;GRAP;STAP1;GRB7|
GRB7 has several biochemical functions, for example, RNA binding, SH3/SH2 adaptor activity, identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GRB7 itself. We selected most functions GRB7 had, and list some proteins which have the same functions with GRB7. You can find most of the proteins on our site.
|SH3/SH2 adaptor activity||TOB1;SH2D2A;LAT;CRKL;SLA2;ARHGAP1;CHN2;SH2D3A;SH3BP2|
|identical protein binding||HTT;FHOD1;DHX8;MDM2;GOT1L1;MCIN;APPL1;AMOTL2;PTPRG|
|protein kinase binding||PEBP1;PTPN1;SFN;PRKRIP1;SNAP91;PRKACA;USP37;H2AFY;CCNA2|
GRB7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GRB7 here. Most of them are supplied by our site. Hope this information will be useful for your research of GRB7.
ERBB2; ERBB3; KIT; RND1
Murray, JC; Aldeghaither, D; et al. c-Abl Modulates Tumor Cell Sensitivity to Antibody-Dependent Cellular Cytotoxicity. CANCER IMMUNOLOGY RESEARCH 2:1186-1198(2014).
Pogue-Geile, KL; Kim, C; et al. Predicting Degree of Benefit From Adjuvant Trastuzumab in NSABP Trial B-31. JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE 105:1782-1788(2013).