Human GRB7 Knockdown Cell Lysate

• Cat.No.: GRB7-185HKCL
• Product Overview: WB-validated GRB7 Knockdown HeLa Cell Lysate

Specification

• Species: Human
• Source: HeLa
• Tag: Non
• Description: The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. The protein plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK). Several transcript variants encoding two different isoforms have been found for this gene.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 60 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HeLa cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HeLa cell lysate 1 vial of 100 μg GRB7 KD HeLa cell lysate
• Protein Families: Druggable Genome, Embryonic stem cells, Stem cell - Pluripotency
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: GRB7 growth factor receptor-bound protein 7 [ Homo sapiens (human) ]
• Official Symbol: GRB7
• Synonyms: GRB7; growth factor receptor-bound protein 7; B47; GRB7 adapter protein; epidermal growth factor receptor GRB-7
• Gene ID: 2886
• mRNA Refseq: NM_001030002
• Protein Refseq: NP_001025173
• MIM: 601522
• UniProt ID: Q14451