GRB7-6971H
Optional Service: Optional requirements on this protein
Product Overview :
Recombinant full-length human GRB7 was expressed by E.coli using an N-terminal GST tag.
Description :
GRB7 or growth factor receptor-bound protein 7 belongs to a small family of adapter proteins which interact with a number of receptor tyrosine kinases and signaling molecules. GRB7 encodes a growth factor receptor-binding protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors.GRB7 is highly expressed in liver and kidney. GRB7 isoforms are involved in cell invasion and metastatic progression of human esophageal carcinomas. GRB7 plays an important role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK).
Source :
E. coli
Species :
Human
Tag :
GST
Form :
Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Molecular Mass :
~91 kDa
Protein length :
Full length
Purity :
>90%
Applications :
Western Blot
Storage :
Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles.
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.